{"id":"W3089801963","doi":"10.1002/prot.26014","title":"Structural fluctuations and mechanical stabilities of the metamorphic protein <scp>RfaH</scp>","year":2020,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Compute Canada","keywords":"CTD; Biophysics; Transcription (linguistics); RNA polymerase; Molecular dynamics; Physics; Chemistry; Biology; RNA; Gene; Biochemistry; Computational chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001899723,0.0002146007,0.0001890538,0.0002100815,0.0004124533,0.0003281479,0.0003725837,0.0002888049,0.0009764633],"category_scores_gemma":[0.0004675414,0.0001961187,0.0002117668,0.0001834491,0.0005730964,0.0002944048,0.0001889963,0.0005132933,0.0001277152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007396677,"about_ca_system_score_gemma":0.0003879069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004091733,"about_ca_topic_score_gemma":0.002945135,"domain_scores_codex":[0.9999239,0.00001192854,0.000003225021,0.00001548254,0.0000252753,0.0000201719],"domain_scores_gemma":[0.9998222,0.00007193829,0.00003170392,0.00001684842,0.00002543859,0.00003193338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0007854053,0.000533822,0.02352779,0.0001995915,0.000268919,0.0005740463,0.0003534328,0.6446356,0.3033128,0.0147373,0.00224352,0.008827784],"study_design_scores_gemma":[0.00005161056,0.000161433,0.01270888,0.000009873966,0.00002063237,0.00006010579,0.00006754745,0.9622751,0.02272421,0.001394868,0.0004904416,0.00003528195],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980768,0.00006073174,0.0009778792,0.00006024234,0.000005247277,0.000003097686,0.00007623244,0.00002898519,0.0007108424],"genre_scores_gemma":[0.9991252,0.0000387935,0.0005078539,0.00001488049,0.000001997608,0.00000819214,0.0001452709,0.00001528612,0.0001423931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004091733,"threshold_uncertainty_score":0.008135855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01218510104353187,"score_gpt":0.1970749672278255,"score_spread":0.1848898661842936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}