{"id":"W3089908790","doi":"10.1093/molehr/gaaa064","title":"Sex-specific epigenetic profile of inner cell mass of mice conceived <i>in vivo</i> or by IVF","year":2020,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; University of California Institute for Mexico and the United States; National Institutes of Health; Consejo Nacional de Ciencia y Tecnología; National Center for Research Resources; Lalor Foundation","keywords":"Biology; Epigenetics; DNA methylation; Differentially methylated regions; Chromatin; Transcriptome; Bisulfite sequencing; Genetics; Embryo; Epigenomics; Gene expression; Cell biology; Andrology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002309934,0.0001628968,0.0002427096,0.000048865,0.00003358068,0.000008569364,0.0001590151,0.0001401238,0.00006002968],"category_scores_gemma":[0.00005727045,0.0001659338,0.00008293266,0.0002084175,0.00009795274,0.000003723687,0.00005242701,0.00009020464,0.000002680309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001208617,"about_ca_system_score_gemma":0.00003374232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002214203,"about_ca_topic_score_gemma":0.000004477323,"domain_scores_codex":[0.9983752,0.0001350138,0.0004658014,0.0006602486,0.0001889853,0.0001747596],"domain_scores_gemma":[0.9990589,0.000005814778,0.0002488606,0.0004897625,0.0001372737,0.00005940502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001057984,0.00009423641,0.0006426295,0.00009081767,0.00001711057,0.000002716463,0.0001628347,0.0006780273,0.9966573,0.00001395427,0.000512862,0.00102169],"study_design_scores_gemma":[0.0005934172,0.0005297486,0.0002476173,0.00001102176,0.00001442449,6.933878e-7,0.00008747921,0.0000387207,0.9852881,0.00007131785,0.01294396,0.0001734474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883484,0.005144769,0.004983613,0.000135666,0.00008270102,0.0003899554,0.0000302661,0.000009335493,0.0008752867],"genre_scores_gemma":[0.997264,0.000393339,0.001279828,0.00004599274,0.0001173684,0.00002133083,0.0001348944,0.00003432051,0.0007088883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01243109,"threshold_uncertainty_score":0.6766585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01488363994638564,"score_gpt":0.2420608389040566,"score_spread":0.227177198957671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}