{"id":"W3089908790","doi":"10.1093/molehr/gaaa064","title":"Sex-specific epigenetic profile of inner cell mass of mice conceived <i>in vivo</i> or by IVF","year":2020,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; University of California Institute for Mexico and the United States; National Institutes of Health; Consejo Nacional de Ciencia y Tecnología; National Center for Research Resources; Lalor Foundation","keywords":"Biology; Epigenetics; DNA methylation; Differentially methylated regions; Chromatin; Transcriptome; Bisulfite sequencing; Genetics; Embryo; Epigenomics; Gene expression; Cell biology; Andrology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001690598,0.0002258371,0.0003040284,0.0006508395,0.0001715251,0.0003819511,0.0001877468,0.0003218238,0.002483544],"category_scores_gemma":[0.0001584197,0.0002484427,0.0003319235,0.0001491087,0.0002798658,0.0001521448,0.0002656089,0.0007196293,0.0004808327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000199192,"about_ca_system_score_gemma":0.0001204085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007229649,"about_ca_topic_score_gemma":0.001067733,"domain_scores_codex":[0.9997969,0.00001933051,0.0000156318,0.00008557499,0.00004570145,0.00003696716],"domain_scores_gemma":[0.9997445,0.00003043824,0.0001069552,0.00002432675,0.00002659995,0.0000673203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001692871,0.00001140942,0.001572529,0.0000174801,0.00000938351,0.00004504522,0.00003814327,0.00001818153,0.996751,0.00005072247,0.00004831422,0.001268549],"study_design_scores_gemma":[0.00004505007,0.00052354,0.2320793,0.00003403678,0.00009358524,0.000797003,0.0001823482,0.0007439002,0.7610488,0.0001303746,0.004287357,0.00003458169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881598,0.002191315,0.003058147,0.0001213386,0.00004409791,0.00003893156,0.003840836,0.000147023,0.002398631],"genre_scores_gemma":[0.985015,0.001159592,0.001946251,0.0002232343,0.00002436311,0.0001250653,0.003147869,0.0001673589,0.008191355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002483544,"threshold_uncertainty_score":0.008308291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01488363994638564,"score_gpt":0.2420608389040566,"score_spread":0.227177198957671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}