{"id":"W3089910952","doi":"10.3390/cells9102240","title":"Urine-Derived Epithelial Cell Lines: A New Tool to Model Fragile X Syndrome (FXS)","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Azrieli Foundation","keywords":"Fragile X syndrome; FMR1; Fragile x; Urine; Cell culture; Autism; Cell; Cytoplasm; Biology; Messenger RNA; Intellectual disability; Cell biology; Medicine; Pathology; Genetics; Gene; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006450032,0.0005396105,0.0006254695,0.0008043986,0.0005222176,0.0006966999,0.000618535,0.0008685655,0.001568505],"category_scores_gemma":[0.0004064762,0.0002767188,0.0006895472,0.0005295262,0.0003986919,0.0004017358,0.0007091387,0.001988547,0.001142789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003298268,"about_ca_system_score_gemma":0.0003695084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00113527,"about_ca_topic_score_gemma":0.001492463,"domain_scores_codex":[0.9990864,0.0002205049,0.000123017,0.00017503,0.0002884928,0.000106641],"domain_scores_gemma":[0.9996308,0.00007907888,0.00005634727,0.00009849158,0.00007818106,0.00005711922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002034759,0.0002434257,0.001250178,0.000217649,0.00002782211,0.0004800109,0.0002003343,0.0004658032,0.9888475,0.001192284,0.000906612,0.005964935],"study_design_scores_gemma":[0.0000766377,0.001517821,0.006020901,0.00007937371,0.0001219356,0.002942475,0.0002519635,0.006761471,0.9247465,0.0007025254,0.05672542,0.00005299509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7633424,0.01028191,0.1940461,0.00207704,0.00148924,0.001582368,0.01220279,0.001614337,0.01336371],"genre_scores_gemma":[0.8776408,0.00717484,0.08691598,0.0008294589,0.0001504439,0.001544525,0.01163594,0.0002815819,0.01382654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001568505,"threshold_uncertainty_score":0.005247116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01165815683222001,"score_gpt":0.2082832574397521,"score_spread":0.196625100607532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}