{"id":"W3090114622","doi":"10.3390/cancers12102827","title":"Impact of Intercurrent Introduction of Steroids on Clinical Outcomes in Advanced Non-Small-Cell Lung Cancer (NSCLC) Patients under Immune-Checkpoint Inhibitors (ICI)","year":2020,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cilag; Loxo Oncology; Takeda Oncology; Sierra Oncology; Ipsen; Oryzon Genomics; Eisai; Daiichi-Sankyo; Novartis Pharma; Glenmark Pharmaceuticals; BeiGene; Clovis Oncology; Les Laboratories Pierre Fabre; AstraZeneca; Novocure; Pfizer; Incyte; Merck KGaA; Taiho Pharmaceutical; Genentech; Institut Gustave-Roussy; Daiichi Sankyo Europe; Servier; Gilead Sciences; Exelixis; Sanofi; GlaxoSmithKline; Spectrum Pharmaceuticals; Amgen; Celgene; Ignyta; Eli Lilly and Company; Samsung; Bristol-Myers Squibb","keywords":"Medicine; Lung cancer; Internal medicine; Prednisone; Cancer; Gastroenterology; Retrospective cohort study; Oncology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002120172,0.000255935,0.0007667453,0.0001491314,0.00001834897,0.000005403956,0.0001371108,0.0001238628,0.0001785842],"category_scores_gemma":[0.00007480545,0.0002023964,0.0005584031,0.0003692347,0.000143666,0.00007978643,0.00004725087,0.0003551145,0.000002054444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001911775,"about_ca_system_score_gemma":0.0007607324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001578992,"about_ca_topic_score_gemma":0.0001040058,"domain_scores_codex":[0.9978164,0.00006787357,0.001165227,0.0004073958,0.0002744324,0.0002686298],"domain_scores_gemma":[0.9988339,0.00006050681,0.0005079707,0.0003136324,0.0001501672,0.0001338309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00996779,0.0003811107,0.9222369,0.0003393527,0.0005152037,0.000001679267,0.001540874,0.00220805,0.03734762,0.000001080512,0.001252413,0.02420789],"study_design_scores_gemma":[0.01362401,0.004650402,0.9438792,0.0006541366,0.0001358682,3.904273e-7,0.0005976222,0.0004732771,0.0355173,0.000001925509,0.0002122049,0.0002536197],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960485,0.0009705477,0.00004843399,0.0006457606,0.001330187,0.000778018,0.00005075044,0.00001758134,0.0001102021],"genre_scores_gemma":[0.9984258,0.0008004584,0.00004574155,0.0003289842,0.0002458707,0.00004099559,0.00003280833,0.00003376482,0.00004560466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02395427,"threshold_uncertainty_score":0.8253485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03137322458875203,"score_gpt":0.3517524092990704,"score_spread":0.3203791847103184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}