{"id":"W3090114622","doi":"10.3390/cancers12102827","title":"Impact of Intercurrent Introduction of Steroids on Clinical Outcomes in Advanced Non-Small-Cell Lung Cancer (NSCLC) Patients under Immune-Checkpoint Inhibitors (ICI)","year":2020,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cilag; Loxo Oncology; Takeda Oncology; Sierra Oncology; Ipsen; Oryzon Genomics; Eisai; Daiichi-Sankyo; Novartis Pharma; Glenmark Pharmaceuticals; BeiGene; Clovis Oncology; Les Laboratories Pierre Fabre; AstraZeneca; Novocure; Pfizer; Incyte; Merck KGaA; Taiho Pharmaceutical; Genentech; Institut Gustave-Roussy; Daiichi Sankyo Europe; Servier; Gilead Sciences; Exelixis; Sanofi; GlaxoSmithKline; Spectrum Pharmaceuticals; Amgen; Celgene; Ignyta; Eli Lilly and Company; Samsung; Bristol-Myers Squibb","keywords":"Medicine; Lung cancer; Internal medicine; Prednisone; Cancer; Gastroenterology; Retrospective cohort study; Oncology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007957849,0.0001725367,0.0003104767,0.0003682723,0.0002946595,0.0006835196,0.0002098745,0.0003002844,0.0007718141],"category_scores_gemma":[0.002766185,0.00009818822,0.0004785157,0.0005868459,0.0002395452,0.0003607729,0.0003103843,0.0006013795,0.0001520419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004460026,"about_ca_system_score_gemma":0.0003145555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001039391,"about_ca_topic_score_gemma":0.002131289,"domain_scores_codex":[0.9993012,0.0002106274,0.00009973968,0.0001233427,0.0001479329,0.0001171579],"domain_scores_gemma":[0.9946873,0.001063059,0.003207592,0.0001613928,0.0003049539,0.0005756313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003583612,0.0000181386,0.9975921,0.000009343617,0.00005354855,0.00003580695,0.00001407942,0.00003409249,0.0001142355,0.000003632145,0.00003247571,0.001734339],"study_design_scores_gemma":[0.000008746893,0.0002120278,0.9992036,0.000005401699,0.0000473773,0.0002039351,0.00003457042,0.00007154031,0.00008246719,0.000007110659,0.0001211811,0.000002102163],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984967,0.0009642636,0.00003608604,0.00003299116,0.000007759226,0.000004075934,0.0001929016,0.000001745299,0.0002635092],"genre_scores_gemma":[0.9996374,0.0001045471,0.0000181122,0.00001700819,0.00001217156,0.000002637315,0.0001730405,7.243457e-7,0.00003445448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001039391,"threshold_uncertainty_score":0.004208565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03137322458875203,"score_gpt":0.3517524092990704,"score_spread":0.3203791847103184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}