{"id":"W3090370421","doi":"10.1016/j.placenta.2020.09.069","title":"Transgenic expression of human C19MC miRNAs impacts placental morphogenesis","year":2020,"lang":"en","type":"article","venue":"Placenta","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; National Center for Research Resources; National Institutes of Health; Pennsylvania Department of Health","keywords":"Biology; Transgene; Genetically modified mouse; microRNA; Placenta; Gene; Microinjection; Phenotype; Cell biology; Chromosome 19; Genetics; Chromosome; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004984289,0.0001378113,0.0001349991,0.00002198357,0.00004886562,0.000008943463,0.0001698037,0.0001027146,0.0001959506],"category_scores_gemma":[0.00002531068,0.0001374138,0.0001217691,0.00006878768,0.00004446086,0.000004686146,0.00006956105,0.00004297198,0.00001423827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001669187,"about_ca_system_score_gemma":0.0000412973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001110009,"about_ca_topic_score_gemma":0.000006169102,"domain_scores_codex":[0.9991392,0.00005014093,0.0002109804,0.0002744473,0.0001477561,0.0001774132],"domain_scores_gemma":[0.9994749,0.000005118005,0.00009802976,0.0002178182,0.00003045112,0.0001736667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000252426,0.00006732454,0.006580357,0.00006414506,0.00002830604,0.000001446271,0.00009720836,0.0000386537,0.9892582,0.000006549595,0.003526746,0.00007860678],"study_design_scores_gemma":[0.0008950498,0.0001312556,0.007797921,0.00002389995,0.00002874413,0.00000387171,0.00006638967,0.00004069219,0.9890049,0.000004303133,0.001860572,0.0001424073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998347,0.0007391582,0.0002231099,0.0001223776,0.0000454807,0.0001895931,0.00009058354,0.00001535662,0.0002273247],"genre_scores_gemma":[0.9989918,0.00004727381,0.0002423024,0.0001324969,0.0001302112,0.000006187917,0.0003731335,0.00002521555,0.00005135742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001666174,"threshold_uncertainty_score":0.560357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01727232235450572,"score_gpt":0.2567198549223248,"score_spread":0.2394475325678191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}