{"id":"W3090370421","doi":"10.1016/j.placenta.2020.09.069","title":"Transgenic expression of human C19MC miRNAs impacts placental morphogenesis","year":2020,"lang":"en","type":"article","venue":"Placenta","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; National Center for Research Resources; National Institutes of Health; Pennsylvania Department of Health","keywords":"Biology; Transgene; Genetically modified mouse; microRNA; Placenta; Gene; Microinjection; Phenotype; Cell biology; Chromosome 19; Genetics; Chromosome; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003460672,0.0003819415,0.0002517339,0.0005734286,0.0003653394,0.0006139507,0.0003896549,0.0006524175,0.005332668],"category_scores_gemma":[0.0003417292,0.0003523398,0.0003651271,0.0002761116,0.0005862371,0.0003132716,0.0003077161,0.001020271,0.001019818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008279234,"about_ca_system_score_gemma":0.0005441656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002641579,"about_ca_topic_score_gemma":0.002762953,"domain_scores_codex":[0.9995589,0.00005624496,0.00004028358,0.0001167621,0.0001158335,0.0001120093],"domain_scores_gemma":[0.9996743,0.00008055929,0.00008248606,0.00004899718,0.00002899235,0.00008466883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003719956,0.00004781324,0.0002155922,0.00002387609,0.000007380932,0.0001128425,0.00002817386,0.00008305846,0.9970573,0.0007249568,0.0001446015,0.001182492],"study_design_scores_gemma":[0.0000348155,0.000189887,0.001672197,0.000005036538,0.00002470289,0.0002097722,0.00004573925,0.0009990924,0.9919322,0.0001835839,0.004696247,0.000006722096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815609,0.001570638,0.008586968,0.0004871675,0.0003095708,0.00009710063,0.001765672,0.0004633875,0.005158574],"genre_scores_gemma":[0.9879584,0.0005791598,0.00327444,0.0001548706,0.00002761178,0.00007536633,0.0007943613,0.0001594991,0.006976245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005332668,"threshold_uncertainty_score":0.01783961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01727232235450572,"score_gpt":0.2567198549223248,"score_spread":0.2394475325678191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}