{"id":"W3090484741","doi":"10.12688/f1000research.26707.2","title":"The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days","year":2020,"lang":"en","type":"preprint","venue":"F1000Research","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Impact; Ottawa Public Health; McMaster University; University of Toronto","funders":"Sweden-America Foundation; National Institute for Health and Care Research; Universität Basel; Svenska Läkaresällskapet; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Uppsala Universitet; Laura and John Arnold Foundation; National Science Foundation","keywords":"Clinical trial; Medicine; Pandemic; Sample size determination; Randomized controlled trial; Psychological intervention; Coronavirus disease 2019 (COVID-19); Internal medicine; Nursing; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","sts","scholarly_communication","open_science","research_integrity","insufficient_payload"],"consensus_categories":["metaresearch","sts","open_science"],"category_scores_codex":[0.18824,0.0008250279,0.001804799,0.0007339888,0.006168927,0.001229539,0.009705705,0.001003884,0.0007166015],"category_scores_gemma":[0.8085948,0.00037787,0.001534362,0.003815786,0.007775393,0.00006798692,0.03139761,0.02465416,0.00398238],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002655404,"about_ca_system_score_gemma":0.02303303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002729704,"about_ca_topic_score_gemma":0.003037435,"domain_scores_codex":[0.9475781,0.02884123,0.003418676,0.003435691,0.01273773,0.003988547],"domain_scores_gemma":[0.2533018,0.724104,0.0005870186,0.01249032,0.003984177,0.005532682],"domain_codex":null,"domain_gemma":"methods","domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.3230792,0.0004165875,0.009038408,0.0005409155,0.0007455178,0.0004465722,0.001629314,0.0001921478,0.00003075679,0.0003666627,0.6525769,0.01093701],"study_design_scores_gemma":[0.01663527,0.003866638,0.0213746,0.0002801143,0.0001290004,0.000008770682,0.0007266151,0.00102273,0.000006505423,0.005270028,0.9503089,0.000370787],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.03421456,0.002229929,0.0003499018,0.9390206,0.001772412,0.02019841,0.0002511667,0.0003579456,0.001605014],"genre_scores_gemma":[0.7689644,0.03268531,0.0002223373,0.08903992,0.02084149,0.01678948,0.0001291282,0.0005412507,0.07078664],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.8499807,"threshold_uncertainty_score":0.9998673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6316961220153703,"score_gpt":0.6451942227936603,"score_spread":0.01349810077829006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}