{"id":"W3091035804","doi":"10.1016/j.devcel.2020.09.002","title":"Combinatorial Action of Temporally Segregated Transcription Factors","year":2020,"lang":"en","type":"article","venue":"Developmental Cell","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Research Council; Fonds de Recherche du Québec - Santé; National Institutes of Health; Austrian Science Fund; Boehringer Ingelheim","keywords":"Biology; Transcription factor; Transcription (linguistics); Action (physics); Computational biology; Genetics; Cell biology; Evolutionary biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003735212,0.0003446594,0.0003158751,0.0003689072,0.0002068922,0.0007360973,0.0003921991,0.000250488,0.0008903887],"category_scores_gemma":[0.0005288094,0.0003873005,0.0002949532,0.0001943137,0.0004914093,0.0004329875,0.0009383507,0.0006374451,0.0004748905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004456966,"about_ca_system_score_gemma":0.000294136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002062849,"about_ca_topic_score_gemma":0.0006468207,"domain_scores_codex":[0.9994546,0.00005017756,0.00003275033,0.000185978,0.0001939316,0.00008260165],"domain_scores_gemma":[0.9995493,0.0001060038,0.0000931987,0.00009292863,0.00005720032,0.0001013198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004263627,0.000005674625,0.0004021681,0.00001141317,0.000004749822,0.00008037017,0.00001639723,0.0002003217,0.9956664,0.001122612,0.00001693426,0.002430357],"study_design_scores_gemma":[0.00002243138,0.0001311676,0.003539778,0.00000825117,0.00003949909,0.000648231,0.00004609648,0.005946678,0.9850241,0.001131001,0.003443931,0.00001890854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9319541,0.001191876,0.0604868,0.00008012902,0.000042328,0.00004373695,0.0001204872,0.0004004568,0.005680141],"genre_scores_gemma":[0.9853634,0.0002734326,0.01167345,0.00004692191,0.00001813485,0.00003643776,0.0001171765,0.00007049766,0.002400673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008903887,"threshold_uncertainty_score":0.003233731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03230186019262358,"score_gpt":0.253421598847327,"score_spread":0.2211197386547034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}