{"id":"W3091035804","doi":"10.1016/j.devcel.2020.09.002","title":"Combinatorial Action of Temporally Segregated Transcription Factors","year":2020,"lang":"en","type":"article","venue":"Developmental Cell","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Research Council; Fonds de Recherche du Québec - Santé; National Institutes of Health; Austrian Science Fund; Boehringer Ingelheim","keywords":"Biology; Transcription factor; Transcription (linguistics); Action (physics); Computational biology; Genetics; Cell biology; Evolutionary biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004617086,0.00007715516,0.00007944618,0.00001785295,0.00003681677,0.000008075354,0.00008390152,0.00006770097,0.00003365483],"category_scores_gemma":[0.00001502148,0.00007257406,0.00004070956,0.0000768195,0.00002297714,0.000004438236,0.00002725111,0.00005749441,0.000009042159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001431247,"about_ca_system_score_gemma":0.0000810104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002946067,"about_ca_topic_score_gemma":0.000006309708,"domain_scores_codex":[0.9994476,0.00002391678,0.0001315015,0.0001491078,0.0001284351,0.0001194009],"domain_scores_gemma":[0.9997928,0.000002572593,0.00003808728,0.00004354046,0.00003499969,0.00008802498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000128063,0.00003037881,0.007696568,0.0000298512,0.00001333799,0.000001113376,0.000134543,0.000002761899,0.9910355,0.00000847202,0.0005835827,0.0003358553],"study_design_scores_gemma":[0.0005921851,0.0002001695,0.004248617,0.000003323967,0.000002554404,7.471445e-7,0.0003225179,0.00002442474,0.9890062,0.000006535467,0.005508741,0.00008405013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979967,0.00003585239,0.0002338114,0.00005399589,0.0001030776,0.0001022032,0.000008078256,0.000009142539,0.001457179],"genre_scores_gemma":[0.9990725,0.00002456634,0.0002861759,0.00005962214,0.00004460511,0.000002489041,0.000222521,0.000009602396,0.0002779513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004925158,"threshold_uncertainty_score":0.2959484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03230186019262358,"score_gpt":0.253421598847327,"score_spread":0.2211197386547034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}