{"id":"W3091046625","doi":"10.1111/bjd.19574","title":"Tralokinumab for moderate‐to‐severe atopic dermatitis: results from two 52‐week, randomized, double‐blind, multicentre, placebo‐controlled phase III trials (ECZTRA 1 and ECZTRA 2)*","year":2020,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":595,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre de Recherche Dermatologique du Québec Métropolitain; Université Laval; Probity Medical Research; Lynde Centre for Dermatology; University of Toronto","funders":"LEO Pharma","keywords":"Placebo; Atopic dermatitis; Double blind; Medicine; Randomized controlled trial; Physical therapy; Dermatology; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007724968,0.001953153,0.003213601,0.00044274,0.000556192,0.001619556,0.001142149,0.002432162,0.004680507],"category_scores_gemma":[0.004503568,0.000772698,0.003574203,0.0006575696,0.0009747039,0.001259244,0.0003784288,0.002552056,0.0007337669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008772141,"about_ca_system_score_gemma":0.001661959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009681179,"about_ca_topic_score_gemma":0.002912376,"domain_scores_codex":[0.9982069,0.0008838734,0.0002109334,0.0003023406,0.0002004228,0.0001955464],"domain_scores_gemma":[0.9979068,0.0005804463,0.000619914,0.0001899775,0.0002255686,0.0004773908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.924148,0.009428669,0.001238732,0.00454439,0.004899068,0.00006538326,0.0001699651,0.0004407892,0.007293643,0.0001362786,0.003157735,0.04447738],"study_design_scores_gemma":[0.9591829,0.03371046,0.003436461,0.0001478818,0.001764183,0.00005532857,0.00002121825,0.0001207428,0.0003769166,0.00007047314,0.001093131,0.00002040861],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8783116,0.0860353,0.002815601,0.002859737,0.001345612,0.01763267,0.005627267,0.0004541364,0.00491813],"genre_scores_gemma":[0.9361024,0.03297972,0.00445083,0.003396657,0.000871539,0.01460327,0.004146019,0.00008425253,0.00336534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007724968,"threshold_uncertainty_score":0.04085404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04667870606626964,"score_gpt":0.3308195138942538,"score_spread":0.2841408078279842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}