{"id":"W3091046625","doi":"10.1111/bjd.19574","title":"Tralokinumab for moderate‐to‐severe atopic dermatitis: results from two 52‐week, randomized, double‐blind, multicentre, placebo‐controlled phase III trials (ECZTRA 1 and ECZTRA 2)*","year":2020,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":595,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre de Recherche Dermatologique du Québec Métropolitain; Université Laval; Probity Medical Research; Lynde Centre for Dermatology; University of Toronto","funders":"LEO Pharma","keywords":"Placebo; Atopic dermatitis; Double blind; Medicine; Randomized controlled trial; Physical therapy; Dermatology; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009143237,0.0004330803,0.005122462,0.0002441644,0.0002431055,0.000167302,0.00029224,0.0003680238,0.0001647123],"category_scores_gemma":[0.006047627,0.000404786,0.001001292,0.0001680816,0.0002795219,0.0003713375,0.00005838529,0.0006024631,0.00001946343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003608518,"about_ca_system_score_gemma":0.0003513701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007917362,"about_ca_topic_score_gemma":0.00006624615,"domain_scores_codex":[0.9936933,0.00126287,0.003525812,0.0005274112,0.0003750277,0.0006155637],"domain_scores_gemma":[0.9924256,0.004403858,0.001430087,0.0002266522,0.0004981288,0.001015647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9381767,0.0006087595,0.0001788622,0.000166364,0.002436885,0.009440915,0.001290959,0.00008130003,0.0001030663,0.00009562218,0.04135537,0.006065228],"study_design_scores_gemma":[0.9422907,0.0002185299,0.0001270952,0.00053769,0.00295583,0.04370669,0.0004077881,0.004677908,0.001419254,0.0007266107,0.002570315,0.0003616303],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9335757,0.01913999,0.008231684,0.03127382,0.0007431795,0.00577543,0.0006400807,0.0000859932,0.0005341046],"genre_scores_gemma":[0.988566,0.001503987,0.003205454,0.005626228,0.0006201754,0.0001672835,0.0001790837,0.00005060016,0.00008119091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05499027,"threshold_uncertainty_score":0.9998404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04667870606626964,"score_gpt":0.3308195138942538,"score_spread":0.2841408078279842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}