{"id":"W3091134115","doi":"10.1016/j.cjca.2020.07.098","title":"DECREASE IN HEART RATE DURING INITIATION OF AMIODARONE THERAPY CORRELATES STRONGLY WITH ACCUMULATION OF SERUM DESETHYLAMIODARONE CONCENTRATIONS","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Calgary Laboratory Services","funders":"","keywords":"Medicine; Amiodarone; Metabolite; Serum concentration; Internal medicine; Active metabolite; Heart rate; Cardiology; Drug; Endocrinology; Pharmacology; Blood pressure; Atrial fibrillation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003348942,0.00046885,0.0008868719,0.0005642204,0.0001800072,0.0005602665,0.0002159311,0.0005777976,0.0009522426],"category_scores_gemma":[0.004064393,0.0002775527,0.0003093368,0.0004282468,0.0002216866,0.000245509,0.0002225708,0.001588102,0.0003608237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002268434,"about_ca_system_score_gemma":0.0002435269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000852431,"about_ca_topic_score_gemma":0.001388556,"domain_scores_codex":[0.9995216,0.00008592304,0.00006060826,0.0001011774,0.0001644809,0.00006618287],"domain_scores_gemma":[0.9945161,0.001771651,0.002381422,0.0002284194,0.000358238,0.0007441419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005292664,0.00029067,0.9101371,0.00009897964,0.0003112382,0.002024699,0.00020171,0.0002718276,0.06791157,0.00007638153,0.0003747577,0.01300838],"study_design_scores_gemma":[0.00001222396,0.0004888621,0.9949941,0.000006832668,0.00003527965,0.001278615,0.00002420816,0.000283369,0.002626276,0.00001658563,0.0002265867,0.000007139313],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933454,0.0014984,0.001708719,0.0001780189,0.00007075522,0.00003506835,0.0006096367,0.0001233082,0.002430699],"genre_scores_gemma":[0.9975776,0.0003706439,0.0006609018,0.00009751147,0.00008345626,0.00002356721,0.0006564378,0.00001700015,0.0005129203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009522426,"threshold_uncertainty_score":0.00318557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02829303234085054,"score_gpt":0.2692842492071071,"score_spread":0.2409912168662565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}