{"id":"W3091166611","doi":"10.1007/s40744-020-00236-1","title":"Repository Corticotropin Injection for Persistently Active Systemic Lupus Erythematosus: Results from a Phase 4, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial","year":2020,"lang":"en","type":"article","venue":"Rheumatology and Therapy","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals","keywords":"Medicine; Placebo; Prednisone; Internal medicine; Adverse effect; Rash; Glucocorticoid; Randomized controlled trial; Population; Gastroenterology; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001798942,0.001231674,0.002410448,0.0003399289,0.0002923161,0.001096709,0.0006263084,0.001479686,0.005004188],"category_scores_gemma":[0.001360696,0.0003992569,0.001496133,0.000364469,0.0008187246,0.0006694896,0.0002527905,0.001866269,0.0008816599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004991438,"about_ca_system_score_gemma":0.0008960198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000423582,"about_ca_topic_score_gemma":0.0009639399,"domain_scores_codex":[0.9994161,0.0003097125,0.00003900221,0.0001057339,0.00006358541,0.00006585217],"domain_scores_gemma":[0.9992711,0.0002266793,0.0002402092,0.00004721077,0.00005625194,0.00015868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9618101,0.003629246,0.0006555159,0.002488657,0.002152992,0.00006733194,0.00005060789,0.0001844859,0.004332549,0.00009852497,0.001029194,0.02350085],"study_design_scores_gemma":[0.9686762,0.02826223,0.001414358,0.00009783127,0.0005974468,0.00003585674,0.00001237061,0.0001384589,0.0002260063,0.00004726585,0.0004837301,0.000008248481],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9407412,0.04595779,0.001145527,0.001494998,0.001141944,0.004735258,0.001379096,0.0002656874,0.003138544],"genre_scores_gemma":[0.972858,0.01456287,0.002248482,0.001575029,0.0007303444,0.004622493,0.001082139,0.0000295873,0.002291072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005004188,"threshold_uncertainty_score":0.01674068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04255996117976809,"score_gpt":0.3214453549871027,"score_spread":0.2788853938073347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}