{"id":"W3091209026","doi":"10.1093/ehjcvp/pvaa118","title":"REDUCE-IT INTERIM: accumulation of data across prespecified interim analyses to final results","year":2020,"lang":"en","type":"letter","venue":"European Heart Journal - Cardiovascular Pharmacotherapy","topic":"Fatty Acid Research and Health","field":"Nursing","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Interim; Interim analysis; Environmental science; Medicine; Political science; Clinical trial; Internal medicine; Law","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.09148089,0.000818353,0.00246465,0.001036701,0.001468075,0.004062028,0.001869346,0.008967443,0.01053814],"category_scores_gemma":[0.3043994,0.0009191157,0.002702321,0.0009061249,0.001439214,0.002649346,0.001996969,0.01207306,0.004710107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001764526,"about_ca_system_score_gemma":0.006812572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00102268,"about_ca_topic_score_gemma":0.00316568,"domain_scores_codex":[0.9262949,0.05934526,0.004498082,0.001763002,0.006313662,0.001785086],"domain_scores_gemma":[0.6328799,0.3090537,0.01300064,0.02536964,0.01415302,0.005543192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006911866,0.0003128458,0.005585205,0.0006376312,0.0005651144,0.001680974,0.0005285462,0.0006989447,0.0008975646,0.01008573,0.758611,0.2134846],"study_design_scores_gemma":[0.008718865,0.003199435,0.01915273,0.002346335,0.001235448,0.003479389,0.0004703284,0.01248439,0.003713394,0.1165029,0.8284186,0.0002781384],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01555282,0.004615864,0.09429083,0.7807838,0.0469212,0.004518851,0.004659964,0.002540722,0.04611596],"genre_scores_gemma":[0.1242402,0.002211377,0.131964,0.6456737,0.05335111,0.01093669,0.00180287,0.00159612,0.02822406],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.09148089,"threshold_uncertainty_score":0.483803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6569511246349635,"score_gpt":0.5574347546978977,"score_spread":0.09951636993706581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}