{"id":"W3091567899","doi":"10.1016/j.chom.2020.09.004","title":"Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection","year":2020,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; University of Toronto; Hospital for Sick Children","funders":"Institute of Basic Medical Sciences; Leibniz-Gemeinschaft; Canadian Institutes of Health Research; Svenska Läkaresällskapet; Stiftelsen Blanceflor Boncompagni Ludovisi, född Bildt; Canadian HIV Trials Network, Canadian Institutes of Health Research; University of Toronto; Deutsche Forschungsgemeinschaft","keywords":"Phagosome; Biology; Lysosome; Cell biology; Microbiology; Phagocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001148542,0.0002087641,0.0001882052,0.00004309251,0.0001487546,0.00004325989,0.0001546642,0.00018943,0.0001196536],"category_scores_gemma":[0.00005014502,0.0002111348,0.0001751737,0.0001449544,0.00005719473,0.000006509417,0.0002212704,0.0002919152,0.0001572611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002179478,"about_ca_system_score_gemma":0.00004600246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006863591,"about_ca_topic_score_gemma":0.00001285145,"domain_scores_codex":[0.9988483,0.00007142688,0.0002227952,0.000454446,0.00009793029,0.0003051323],"domain_scores_gemma":[0.999423,0.000006265278,0.00008203097,0.0002455739,0.0000668623,0.0001763074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001128308,0.00006594958,0.003650973,0.00005658857,0.00001707148,0.00001111663,0.000122481,0.00002104164,0.9944686,0.00001214132,0.001190093,0.0002711534],"study_design_scores_gemma":[0.0007694894,0.0001352614,0.0117582,0.00001225813,0.00002931712,0.00002415952,0.00003860455,0.00002995192,0.9403297,0.000007506761,0.04661538,0.0002502094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965966,0.001128489,0.0007439041,0.0003529957,0.0003247747,0.0001457522,0.00002873076,0.00005900318,0.0006197996],"genre_scores_gemma":[0.997048,0.0004163915,0.0001910797,0.0007593752,0.000891249,0.00000607763,0.00009640404,0.00003909269,0.0005523286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0541389,"threshold_uncertainty_score":0.8609825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01178286143356591,"score_gpt":0.2271255864552894,"score_spread":0.2153427250217235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}