{"id":"W3091567899","doi":"10.1016/j.chom.2020.09.004","title":"Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection","year":2020,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; University of Toronto; Hospital for Sick Children","funders":"Institute of Basic Medical Sciences; Leibniz-Gemeinschaft; Canadian Institutes of Health Research; Svenska Läkaresällskapet; Stiftelsen Blanceflor Boncompagni Ludovisi, född Bildt; Canadian HIV Trials Network, Canadian Institutes of Health Research; University of Toronto; Deutsche Forschungsgemeinschaft","keywords":"Phagosome; Biology; Lysosome; Cell biology; Microbiology; Phagocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003070391,0.000179628,0.0003132498,0.0002346333,0.0004996458,0.001041225,0.0004025232,0.0006007404,0.001070007],"category_scores_gemma":[0.0003872677,0.000212119,0.0001864072,0.0002105955,0.0003734884,0.000943683,0.000554735,0.0008046536,0.0004566782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001001181,"about_ca_system_score_gemma":0.0004184946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009862535,"about_ca_topic_score_gemma":0.001330452,"domain_scores_codex":[0.9996914,0.00003963133,0.00002278437,0.00005284255,0.00007908087,0.0001142514],"domain_scores_gemma":[0.9997153,0.00004766589,0.00006131719,0.00004592743,0.00004933247,0.00008036139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004771696,0.00001691188,0.0002552599,0.0000172259,0.000004216053,0.00006463431,0.0000212956,0.0000294142,0.9980294,0.0003407748,0.00004635162,0.0006973034],"study_design_scores_gemma":[0.00001396548,0.00007619257,0.009477107,0.000005411167,0.00000890088,0.000254665,0.00007473092,0.001287983,0.9876608,0.0001974222,0.0009353244,0.00000739544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991374,0.002747714,0.00344739,0.0002845155,0.00004863533,0.00001339304,0.0002780673,0.00007325327,0.001733014],"genre_scores_gemma":[0.9977998,0.0001985976,0.0005838646,0.00003772513,0.00001003468,0.000006117704,0.000193837,0.0000150402,0.001154947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001070007,"threshold_uncertainty_score":0.007264078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01178286143356591,"score_gpt":0.2271255864552894,"score_spread":0.2153427250217235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}