{"id":"W3091666079","doi":"10.3390/cells9102214","title":"Progressive Photoreceptor Dysfunction and Age-Related Macular Degeneration-Like Features in rp1l1 Mutant Zebrafish","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates; Natural Sciences and Engineering Research Council of Canada; Government of Alberta; Stollery Children’s Hospital Foundation; Children's Hospital Foundation; Children’s Hospital of Wisconsin Research Institute; University of Alberta; Rare Disease Foundation; Women and Children's Health Research Institute","keywords":"Zebrafish; Macular degeneration; Degeneration (medical); Retinal degeneration; Mutant; Retina; Ophthalmology; Medicine; Biology; Neuroscience; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004449024,0.0001141144,0.00009664849,0.00002194036,0.00004075634,0.00003279443,0.00005898498,0.0001216252,0.00006047945],"category_scores_gemma":[0.00002140564,0.0001057803,0.00003160871,0.00008936351,0.00004967793,0.000004137255,0.00004159365,0.00007124216,0.00001255514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006692699,"about_ca_system_score_gemma":0.00003163566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006941142,"about_ca_topic_score_gemma":0.00001240191,"domain_scores_codex":[0.9993528,0.00003222535,0.0001318845,0.0002714647,0.00007738114,0.0001343165],"domain_scores_gemma":[0.9997837,0.000003468271,0.00004378774,0.0000716309,0.00002557087,0.00007183872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008190482,0.00002184971,0.002035798,0.00001864922,0.00002140473,0.0000273364,0.0002408945,0.00003785689,0.9894074,0.00001388848,0.007250876,0.0008421993],"study_design_scores_gemma":[0.0008848927,0.0001708063,0.004785814,0.00001349065,0.00001252625,0.000006916016,0.0001234566,0.0001223722,0.9736631,0.00003852481,0.01995726,0.0002208551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970483,0.00135132,0.00005934552,0.0002956181,0.0001652198,0.0002408906,0.000004832312,0.00001273724,0.0008217486],"genre_scores_gemma":[0.9980881,0.000158227,0.0003577778,0.000593826,0.00006557491,0.00002164189,0.0002794102,0.0000140909,0.0004213534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01574426,"threshold_uncertainty_score":0.4313594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005117204004502432,"score_gpt":0.2003690001779932,"score_spread":0.1952517961734908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}