{"id":"W3091760426","doi":"10.1038/s41598-020-72903-w","title":"DJ-1 (Park7) affects the gut microbiome, metabolites and the development of innate lymphoid cells (ILCs)","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research; Ontario Brain Institute","funders":"Eberhard Karls Universität Tübingen; Deutsche Forschungsgemeinschaft; EU Joint Programme – Neurodegenerative Disease Research","keywords":"Innate lymphoid cell; Biology; Microbiome; Inflammation; Phenotype; Calprotectin; Immune dysregulation; Immunology; Immune system; Innate immune system; Gut flora; Disease; Metabolome; Metabolomics; Genetics; Bioinformatics; Inflammatory bowel disease; Medicine; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001021556,0.0003745856,0.0002472199,0.000347609,0.0001771268,0.0003027011,0.0001423964,0.000317609,0.001482478],"category_scores_gemma":[0.0001026828,0.0001281497,0.0002874712,0.000129715,0.0002391299,0.0002048039,0.0002054597,0.0005015655,0.0002024293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001857549,"about_ca_system_score_gemma":0.000128147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003288347,"about_ca_topic_score_gemma":0.0005026119,"domain_scores_codex":[0.9998605,0.00002033435,0.00001403072,0.00004005512,0.00002931938,0.00003563711],"domain_scores_gemma":[0.9998318,0.00001390831,0.0000711797,0.000008503732,0.00001550073,0.00005906448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003578087,0.00002752519,0.001434157,0.00005996735,0.00001135292,0.0001430535,0.00001397361,0.00002067085,0.9970481,0.00003519333,0.00004186368,0.0008063509],"study_design_scores_gemma":[0.00003777496,0.001019531,0.08478643,0.0000231959,0.00009456109,0.001929224,0.0002558548,0.0006940749,0.9073936,0.0001909844,0.003559648,0.00001509397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995069,0.002512183,0.001129223,0.0001332686,0.00003945139,0.00001101071,0.0006757759,0.00004298226,0.0003870964],"genre_scores_gemma":[0.9960238,0.0009621186,0.0007919661,0.00009282146,0.00001017582,0.00001661829,0.0004777251,0.00001325186,0.001611561],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001482478,"threshold_uncertainty_score":0.004959404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01509810399041346,"score_gpt":0.2348975893814566,"score_spread":0.2197994853910431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}