{"id":"W3091793191","doi":"10.1101/2020.10.11.335117","title":"A parental transcriptional response to microsporidia infection induces inherited immunity in offspring","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Parasitic Infections and Diagnostics","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Biology; Immunity; Offspring; Immune system; Innate immune system; Acquired immune system; Intrinsic immunity; Intracellular parasite; Pathogen; Microsporidia; Immunology; Genetics; Microbiology; Spore","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001258768,0.000261513,0.0001335682,0.0001567438,0.0001028765,0.0002423123,0.0001512147,0.0002440808,0.002113204],"category_scores_gemma":[0.0001085139,0.0001155513,0.0001722178,0.00006324922,0.0001726512,0.0001055261,0.0003352354,0.0005559174,0.0005198811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000278997,"about_ca_system_score_gemma":0.0001088191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002393507,"about_ca_topic_score_gemma":0.0004037863,"domain_scores_codex":[0.9998887,0.00001423322,0.000007266824,0.00003802263,0.00002881365,0.00002298873],"domain_scores_gemma":[0.9998381,0.00003160167,0.0000467377,0.0000313497,0.00001498862,0.00003717243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001644324,0.00000425338,0.0002727574,0.000008600106,0.000001397943,0.00002672725,0.000007073977,0.000009507056,0.9992768,0.00003476121,0.00001508309,0.0003265014],"study_design_scores_gemma":[0.000007776258,0.0001268636,0.0286559,0.000005112075,0.00001058035,0.0002240325,0.00003044035,0.0004519857,0.9688095,0.00004068042,0.001632264,0.000004853216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939213,0.0004541846,0.002829686,0.00006878009,0.00002755375,0.00001197136,0.0004761821,0.000118695,0.002091566],"genre_scores_gemma":[0.994023,0.0001508156,0.0009952602,0.00004814056,0.000008864082,0.00001464674,0.0004860376,0.00003417175,0.004238934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002113204,"threshold_uncertainty_score":0.007069349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0205978477225558,"score_gpt":0.246348012725271,"score_spread":0.2257501650027152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}