{"id":"W3091793213","doi":"10.4049/immunohorizons.2000080","title":"Caspase-4: A Therapeutic Target for Peptic Ulcer Disease","year":2020,"lang":"en","type":"article","venue":"ImmunoHorizons","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"H2020 Marie Skłodowska-Curie Actions; European Commission","keywords":"Pyroptosis; Inflammasome; Caspase 1; Secretion; Helicobacter pylori; Peptic; Medicine; Disease; Downregulation and upregulation; Peptic ulcer; Immunology; Cancer research; Biology; Inflammation; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006239124,0.0001709407,0.0001353688,0.0000193026,0.0001348858,0.00003065755,0.000225633,0.00007713892,0.00008992624],"category_scores_gemma":[0.00009954713,0.0001651742,0.0002049401,0.00007726665,0.00006242799,0.000005123754,0.00006826999,0.0000749632,0.00007482269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007521513,"about_ca_system_score_gemma":0.0001149514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005118286,"about_ca_topic_score_gemma":0.000001161901,"domain_scores_codex":[0.9991086,0.00003198796,0.0001742437,0.000300685,0.00008020084,0.0003043062],"domain_scores_gemma":[0.9994367,0.00001175534,0.00004812725,0.0003184998,0.00006750436,0.0001174148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001028451,0.0001071692,0.001047432,0.0000686663,0.0003018536,0.000006556989,0.0002482038,0.00008717009,0.9786915,0.0007901838,0.01209453,0.005528325],"study_design_scores_gemma":[0.002383871,0.001731816,0.002884126,0.00001448502,0.0001464432,0.000004143005,0.0004141144,0.0005239047,0.1149091,0.0007213834,0.8755866,0.0006800855],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.949137,0.0166128,0.02120162,0.007236707,0.0006730474,0.001464987,0.000264444,0.0001054967,0.003303885],"genre_scores_gemma":[0.9962806,0.0001378236,0.0003713558,0.001618862,0.0002682166,0.0001444629,0.0003984056,0.00004491874,0.0007353171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8637824,"threshold_uncertainty_score":0.6735607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01478362199968541,"score_gpt":0.2467615394417501,"score_spread":0.2319779174420647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}