{"id":"W3092084717","doi":"10.1139/cjc-2020-0302","title":"Impact of an unusual disulfide transformation on detection of isothermal amplification products","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Reagent; Nucleic acid; Analyte; Oxidizing agent; Combinatorial chemistry; Loop-mediated isothermal amplification; Biochemistry; Molecular biology; Chromatography; DNA; Organic chemistry; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005432356,0.0003588852,0.0002090889,0.0001617172,0.0001768768,0.0003565129,0.0003174782,0.0003722523,0.0007664107],"category_scores_gemma":[0.0008721527,0.000211683,0.0002638086,0.0001576872,0.0002732982,0.0003440375,0.0002480749,0.000587441,0.0002707255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00015358,"about_ca_system_score_gemma":0.0001735081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003564174,"about_ca_topic_score_gemma":0.0005058405,"domain_scores_codex":[0.9995522,0.0001037312,0.00003017155,0.0001182175,0.0001338489,0.00006193623],"domain_scores_gemma":[0.9996264,0.0001269468,0.00008311261,0.00004864454,0.00007568333,0.00003926594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001238543,0.00003368175,0.0003598049,0.00003787794,0.000008635056,0.0001216249,0.00004943386,0.00008150615,0.997439,0.00006960769,0.00003051908,0.001644419],"study_design_scores_gemma":[0.000004003333,0.000260473,0.0006049997,0.000002370824,0.000007406117,0.0001742977,0.00001945674,0.0007397729,0.997645,0.00001987912,0.0005188198,0.00000353016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936259,0.0004356877,0.004576444,0.0001041435,0.00003991419,0.00002899389,0.0000930153,0.0001115978,0.0009843122],"genre_scores_gemma":[0.9965686,0.0002206373,0.002311105,0.00005701826,0.000008896135,0.00001008963,0.00012739,0.00002716833,0.0006690864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007664107,"threshold_uncertainty_score":0.002872944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072369941523242,"score_gpt":0.2061648317434165,"score_spread":0.1954411323281841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}