{"id":"W3092140209","doi":"10.1016/j.ccell.2020.09.009","title":"Dual Checkpoint Blockade in Metastatic Castration-Resistant Prostate Cancer: Just a Gambit or Real CheckMate?","year":2020,"lang":"en","type":"letter","venue":"Cancer Cell","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Pfizer Canada; AstraZeneca Canada","keywords":"Gambit; Blockade; Prostate cancer; Medicine; Cancer research; Dual (grammatical number); Oncology; Cancer; Internal medicine; Computer science; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002832771,0.00058493,0.00120647,0.0005650677,0.002538864,0.00267168,0.001326342,0.03729383,0.009387068],"category_scores_gemma":[0.01136229,0.0004272112,0.001044089,0.0004812566,0.002023773,0.003207698,0.001360437,0.02310361,0.004746873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003897717,"about_ca_system_score_gemma":0.004994234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006887713,"about_ca_topic_score_gemma":0.01829648,"domain_scores_codex":[0.9980465,0.0006898917,0.0001792045,0.0001550012,0.0005928681,0.0003365032],"domain_scores_gemma":[0.9961088,0.00196018,0.0002226447,0.00008674751,0.0004499089,0.001171699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001797804,0.00008377724,0.0005500781,0.00005910575,0.0000170214,0.001693004,0.00006191478,0.0001225738,0.0002468788,0.004166525,0.9675607,0.0252586],"study_design_scores_gemma":[0.0003622267,0.0002379747,0.001293152,0.0003785074,0.00003840614,0.002058722,0.0002982709,0.0008845062,0.0002270517,0.01203528,0.9821187,0.00006722801],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0004978839,0.002161119,0.00008834062,0.9808397,0.01041811,0.00001121876,0.00005364331,0.00002461276,0.005905313],"genre_scores_gemma":[0.007143041,0.002732218,0.0003317793,0.9398341,0.0340404,0.00003773122,0.00005376161,0.00002487075,0.01580198],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03729383,"threshold_uncertainty_score":0.03140289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0787338536318727,"score_gpt":0.3547603991219523,"score_spread":0.2760265454900797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}