{"id":"W3092180222","doi":"10.1101/2020.10.08.332551","title":"Humans surviving cholera develop antibodies against <i>Vibrio cholerae</i> O-specific polysaccharide that inhibit pathogen motility","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Fogarty International Center; International Centre for Diarrhoeal Disease Research, Bangladesh; Styrelsen för Internationellt Utvecklingssamarbete; National Institute of Allergy and Infectious Diseases; Global Affairs Canada; Robert Wood Johnson Foundation","keywords":"Vibrio cholerae; Polyclonal antibodies; Microbiology; Cholera; Biology; Antibody; Motility; Cholera toxin; Flagellin; Vibrionaceae; El Tor; Pathogen; Bacteria; Immunology; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001074233,0.0003373862,0.0002003704,0.0001463823,0.0001559697,0.0002235873,0.0001118122,0.0004814838,0.00248818],"category_scores_gemma":[0.0002529255,0.0001110233,0.0001693675,0.00006035098,0.0002258289,0.0001461158,0.0001099684,0.0003311116,0.0003573767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001687712,"about_ca_system_score_gemma":0.0001058311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009682748,"about_ca_topic_score_gemma":0.0005544143,"domain_scores_codex":[0.9999313,0.00001086054,0.000003197537,0.0000170215,0.00001164071,0.00002591605],"domain_scores_gemma":[0.9998838,0.00002125382,0.00003451523,0.00001022927,0.00002439878,0.00002576632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001577299,0.0009452836,0.1905558,0.0003424126,0.0001603622,0.002361041,0.0003122631,0.000263386,0.757583,0.0005969265,0.002951549,0.04235072],"study_design_scores_gemma":[0.0001665984,0.009040236,0.8841313,0.0001472905,0.000223991,0.01527366,0.0003420172,0.0009054667,0.0732554,0.0004917818,0.01599471,0.0000276035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935635,0.001253531,0.000555985,0.0002175328,0.00003302972,0.00003002341,0.0001138474,0.00004765151,0.004184869],"genre_scores_gemma":[0.9984061,0.0002818926,0.000227301,0.0001797796,0.00001687927,0.000006965182,0.00008954348,0.000004337493,0.0007871771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00248818,"threshold_uncertainty_score":0.008323729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02932946491818391,"score_gpt":0.243555103829407,"score_spread":0.2142256389112231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}