{"id":"W3092183154","doi":"10.1038/s41375-020-01051-x","title":"Changing paradigms in diagnosis and treatment of monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM)","year":2020,"lang":"en","type":"review","venue":"Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Monoclonal gammopathy of undetermined significance; Multiple myeloma; Medicine; Disease; Risk stratification; Bone marrow; Monoclonal; Oncology; Immunology; Pathology; Internal medicine; Monoclonal antibody; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00141022,0.0006928843,0.001816171,0.002196692,0.0002664405,0.001351391,0.001044456,0.001510957,0.005162373],"category_scores_gemma":[0.002520173,0.0002570903,0.0008800954,0.002183194,0.0005777354,0.001710442,0.0008054329,0.002608507,0.001251784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001145917,"about_ca_system_score_gemma":0.002356081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00263935,"about_ca_topic_score_gemma":0.006575895,"domain_scores_codex":[0.9996081,0.0001053501,0.00006872878,0.00005478878,0.0001250077,0.00003798725],"domain_scores_gemma":[0.9987702,0.000769694,0.0001558912,0.00002005838,0.0002185598,0.00006565027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001410957,0.00005901674,0.000160101,0.03729154,0.0001934728,0.0001028014,0.00006278118,0.0003158271,0.0005082042,0.005529921,0.04040582,0.9152294],"study_design_scores_gemma":[0.00008936659,0.000149021,0.0008699821,0.02048907,0.0005237208,0.0005927766,0.00009820102,0.0001191117,0.0001356546,0.004197215,0.9727102,0.00002566099],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002447202,0.9992056,0.00003494693,0.000364487,0.0001297493,0.000001808401,0.000009717544,0.00000250745,0.0002266517],"genre_scores_gemma":[0.0002642632,0.9988247,0.0001111674,0.0004650585,0.0001769487,0.000003316966,0.00001685204,6.996452e-7,0.0001370067],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005162373,"threshold_uncertainty_score":0.01726979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07765431955879935,"score_gpt":0.3379218021911808,"score_spread":0.2602674826323814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}