{"id":"W3092209489","doi":"10.1002/art.41552","title":"MicroRNA‐34a‐5p Promotes Joint Destruction During Osteoarthritis","year":2020,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; Alberta Bone and Joint Health Institute; University of Calgary; University of Toronto; University Health Network","funders":"Canada Research Chairs","keywords":"Osteoarthritis; microRNA; Joint (building); Medicine; Biology; Pathology; Genetics; Engineering; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003007634,0.0004560335,0.0004543854,0.000588985,0.0002553271,0.0004602508,0.0001500337,0.0004115975,0.0009391444],"category_scores_gemma":[0.0003524445,0.0002682144,0.0004441504,0.0002467911,0.0003689345,0.0002017517,0.00035245,0.0004583046,0.0004134357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001788937,"about_ca_system_score_gemma":0.0002306688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002130614,"about_ca_topic_score_gemma":0.0002815771,"domain_scores_codex":[0.9997054,0.00005700061,0.00003354144,0.00006268165,0.00009338187,0.0000479436],"domain_scores_gemma":[0.9997593,0.00002426323,0.0001246075,0.000009417011,0.00002960153,0.00005286912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008266006,0.00004748756,0.00505664,0.0001447361,0.00002371064,0.0004696442,0.00006060686,0.00005246877,0.9902055,0.00004785818,0.00008326413,0.002981422],"study_design_scores_gemma":[0.0001930963,0.003432652,0.4185187,0.0001123042,0.0002955817,0.006317453,0.0004822219,0.00171206,0.5619064,0.0002709272,0.006715467,0.00004309797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874692,0.008967463,0.002283046,0.0001184472,0.00004996324,0.00003371843,0.0002142848,0.0001097913,0.0007541624],"genre_scores_gemma":[0.9961115,0.001508598,0.001241965,0.00006225989,0.00002700767,0.00003578433,0.0001696734,0.00001079972,0.0008325091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009391444,"threshold_uncertainty_score":0.003141701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01460354960283661,"score_gpt":0.2217248262648264,"score_spread":0.2071212766619898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}