{"id":"W3092209489","doi":"10.1002/art.41552","title":"MicroRNA‐34a‐5p Promotes Joint Destruction During Osteoarthritis","year":2020,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; Alberta Bone and Joint Health Institute; University of Calgary; University of Toronto; University Health Network","funders":"Canada Research Chairs","keywords":"Osteoarthritis; microRNA; Joint (building); Medicine; Biology; Pathology; Genetics; Engineering; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000846475,0.0003856625,0.0008969484,0.0001490836,0.0002715839,0.00004988363,0.0001101822,0.0002710648,0.0006941709],"category_scores_gemma":[0.0001773074,0.0004110471,0.0002433846,0.0002762402,0.0002055472,0.0002491465,0.0001114111,0.0003566158,0.0008664337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005973179,"about_ca_system_score_gemma":0.0001129076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004224946,"about_ca_topic_score_gemma":0.0001011345,"domain_scores_codex":[0.9974988,0.00009542123,0.0006931029,0.0007295731,0.0002690606,0.0007140319],"domain_scores_gemma":[0.9987957,0.00003614188,0.000184428,0.0003563654,0.0001263208,0.0005009718],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009512144,0.0003423566,0.0456793,0.0004673421,0.0001754266,0.003630791,0.002435786,0.00000137121,0.6120158,0.005177006,0.0008008018,0.3283228],"study_design_scores_gemma":[0.05040714,0.01492255,0.01589181,0.002875288,0.0002494623,0.06372443,0.001507266,0.00005585404,0.8337284,0.002609749,0.01236777,0.001660236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869422,0.005509732,0.00007566001,0.00442473,0.0005579884,0.0009017238,0.00002911809,0.0005062253,0.001052567],"genre_scores_gemma":[0.9942934,0.001311058,0.003288276,0.0005202756,0.0001296922,0.0001229894,0.0001136207,0.00008284079,0.0001378416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3266625,"threshold_uncertainty_score":0.9999115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01460354960283661,"score_gpt":0.2217248262648264,"score_spread":0.2071212766619898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}