{"id":"W3092253370","doi":"10.1128/mbio.01568-20","title":"Decoding the Architecture of the Varicella-Zoster Virus Transcriptome","year":2020,"lang":"en","type":"article","venue":"mBio","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Daiichi Sankyo Europe; National Institute of Allergy and Infectious Diseases; National Institute for Health and Care Research; National Institute of General Medical Sciences; School of Medicine, New York University; National Institutes of Health; Daiichi Sankyo Foundation of Life Science; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; University College London; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; York University; Takeda Science Foundation","keywords":"Biology; Varicella zoster virus; Transcriptome; Virology; Gene; Transcription (linguistics); Genome; Gene expression; Virus; Genetics; Transactivation; RNA; RNA polymerase; Computational biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004241955,0.0000683203,0.0001046259,0.00001296111,0.00008165969,0.000007480328,0.00007279386,0.00003500365,0.0002726907],"category_scores_gemma":[0.00001907969,0.00003088229,0.0001083792,0.0001753479,0.00004788515,0.00001040434,0.00001887642,0.0001438527,0.00004537347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001361001,"about_ca_system_score_gemma":0.00002301089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007917408,"about_ca_topic_score_gemma":0.00002416183,"domain_scores_codex":[0.9995707,0.0000307707,0.0001047068,0.00009408055,0.000103104,0.0000966278],"domain_scores_gemma":[0.9996967,0.00002949833,0.00002756768,0.0001840502,0.00001673389,0.00004539005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007191984,0.001358451,0.1078726,0.0004868128,0.0019676,0.0001131952,0.03287154,0.000155953,0.3783256,0.001810831,0.0118248,0.4624935],"study_design_scores_gemma":[0.002748895,0.0004157034,0.06473039,0.0001124339,0.0006181605,0.00008353014,0.0002437319,0.0002530272,0.1372517,0.0003489343,0.7930151,0.0001783613],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683517,0.0002536568,0.0006529476,0.01136826,0.0001989655,0.000340906,0.00001737281,0.00003326488,0.01878296],"genre_scores_gemma":[0.9962817,0.00001113046,0.000109348,0.003072609,0.00007580766,0.00000687215,0.000001256546,0.000009069818,0.0004321619],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7811903,"threshold_uncertainty_score":0.2985772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02531431522702729,"score_gpt":0.2490442870455828,"score_spread":0.2237299718185555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}