{"id":"W3092253370","doi":"10.1128/mbio.01568-20","title":"Decoding the Architecture of the Varicella-Zoster Virus Transcriptome","year":2020,"lang":"en","type":"article","venue":"mBio","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Daiichi Sankyo Europe; National Institute of Allergy and Infectious Diseases; National Institute for Health and Care Research; National Institute of General Medical Sciences; School of Medicine, New York University; National Institutes of Health; Daiichi Sankyo Foundation of Life Science; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; University College London; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; York University; Takeda Science Foundation","keywords":"Biology; Varicella zoster virus; Transcriptome; Virology; Gene; Transcription (linguistics); Genome; Gene expression; Virus; Genetics; Transactivation; RNA; RNA polymerase; Computational biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001432957,0.0002069047,0.0002778227,0.0004266788,0.0002636073,0.001025069,0.0001212495,0.0001957695,0.001010213],"category_scores_gemma":[0.0002917105,0.0002004709,0.0002520466,0.0004224807,0.0001426202,0.0005317085,0.0002911582,0.0005917264,0.0007310779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002785834,"about_ca_system_score_gemma":0.0004670187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008437326,"about_ca_topic_score_gemma":0.002331501,"domain_scores_codex":[0.9999076,0.00001355282,0.000006150667,0.00003630027,0.00001693515,0.00001939815],"domain_scores_gemma":[0.9998971,0.00003000346,0.00001969408,0.00001388481,0.00002533837,0.00001395384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000145295,0.00000682857,0.003022625,0.000182035,0.000009668707,0.00007459206,0.000207729,0.000588659,0.9761037,0.00088649,0.0002338734,0.01853851],"study_design_scores_gemma":[0.00002376601,0.0004621487,0.158422,0.0003485908,0.0002034134,0.001348421,0.00156481,0.02281276,0.718969,0.006810463,0.08895784,0.00007684715],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8750657,0.0177761,0.08309015,0.0005832633,0.0001349457,0.00009935575,0.01362894,0.0007007357,0.008920822],"genre_scores_gemma":[0.8951548,0.01642368,0.06101943,0.0002650392,0.0001153011,0.0001178507,0.02066163,0.000412782,0.005829398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001025069,"threshold_uncertainty_score":0.003379464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02531431522702729,"score_gpt":0.2490442870455828,"score_spread":0.2237299718185555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}