{"id":"W3092266223","doi":"10.7554/elife.61960","title":"Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis","year":2020,"lang":"en","type":"article","venue":"eLife","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Japan Society for the Promotion of Science","keywords":"Pannexin; Apoptosis; Cell biology; Dynamics (music); Programmed cell death; Cell; Adenosine triphosphate; Biology; Chemistry; Biophysics; Computational biology; Physics; Gap junction; Biochemistry; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005949779,0.0001548925,0.0002021661,0.00002366301,0.00004159371,0.000009017421,0.0001829599,0.000165288,0.00004369819],"category_scores_gemma":[0.0001106946,0.0001484421,0.0001195406,0.000120256,0.000109409,0.000002087258,0.0001406555,0.00008813588,0.00001732002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001371459,"about_ca_system_score_gemma":0.00003829116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002010807,"about_ca_topic_score_gemma":0.00002318565,"domain_scores_codex":[0.9989772,0.00004780363,0.0002641563,0.0003424597,0.0001003853,0.0002679911],"domain_scores_gemma":[0.9994118,0.00001069516,0.00009602608,0.0002415974,0.000111805,0.0001280874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002384379,0.0001299421,0.007115675,0.00008442587,0.0000541987,0.000003458649,0.0002240774,0.00001653723,0.9888417,0.00003293268,0.0002647244,0.002993913],"study_design_scores_gemma":[0.00087574,0.0007596556,0.001076452,0.000007786339,0.00001886131,0.000004322049,0.000260993,0.0002542495,0.9702256,0.000004415327,0.02628981,0.0002221383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975192,0.0002871109,0.0003215951,0.001026906,0.00007330273,0.0001676725,0.00006951032,0.000030886,0.0005038372],"genre_scores_gemma":[0.9984485,0.00007338495,0.0004349926,0.0003982643,0.000139965,0.00001199722,0.0002532614,0.00002108801,0.0002185831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02602508,"threshold_uncertainty_score":0.6053295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01406176032074498,"score_gpt":0.2173912039979851,"score_spread":0.2033294436772401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}