{"id":"W3092266223","doi":"10.7554/elife.61960","title":"Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis","year":2020,"lang":"en","type":"article","venue":"eLife","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Japan Society for the Promotion of Science","keywords":"Pannexin; Apoptosis; Cell biology; Dynamics (music); Programmed cell death; Cell; Adenosine triphosphate; Biology; Chemistry; Biophysics; Computational biology; Physics; Gap junction; Biochemistry; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001573779,0.000133923,0.0003363492,0.0001246792,0.0001289022,0.0003186047,0.0002963431,0.0003344947,0.0005653317],"category_scores_gemma":[0.0002035436,0.0001028788,0.0001407032,0.0001379132,0.0002083685,0.0004238444,0.0002271179,0.0005861246,0.0001918821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004467457,"about_ca_system_score_gemma":0.0001192818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004569203,"about_ca_topic_score_gemma":0.000581044,"domain_scores_codex":[0.9998788,0.000009986011,0.000005749926,0.00004070562,0.00003829848,0.00002649579],"domain_scores_gemma":[0.9998938,0.00002614078,0.00002525182,0.00001219781,0.00002270031,0.00002000115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009685006,0.00001447873,0.0004239243,0.00002350664,0.0000041965,0.00009057247,0.00005981002,0.0002266151,0.996822,0.0001505462,0.0000475448,0.002039952],"study_design_scores_gemma":[0.00001360243,0.00009574898,0.008447,0.00000494013,0.000007487991,0.0001957488,0.00009531005,0.01078921,0.9791574,0.0002063109,0.0009756263,0.00001153265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920218,0.000606546,0.006453826,0.0000752934,0.00001706571,0.00001040129,0.0001784352,0.00006533504,0.0005713282],"genre_scores_gemma":[0.9957303,0.0003602494,0.002775852,0.00003156152,0.000005414618,0.00002459238,0.0001284161,0.00001355442,0.0009300276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005653317,"threshold_uncertainty_score":0.00324142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01406176032074498,"score_gpt":0.2173912039979851,"score_spread":0.2033294436772401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}