{"id":"W3092274335","doi":"10.3389/fgene.2020.01022","title":"Insulin-Independent and Dependent Glucose Transporters in Brain Mural Cells in CADASIL","year":2020,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; NIHR Newcastle Biomedical Research Centre; Newcastle upon Tyne Hospitals NHS Foundation Trust; Stiftelsen för Gamla Tjänarinnor; Engineering and Physical Sciences Research Council; Stiftelsen Olle Engkvist Byggmästare; National Institute for Health and Care Research; Alzheimer's Society; Economic and Social Research Council; Gun och Bertil Stohnes Stiftelse","keywords":"CADASIL; GLUT4; Vascular smooth muscle; Leukoencephalopathy; Biology; Internal medicine; Endocrinology; Glucose transporter; Insulin; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002079124,0.0002192264,0.0004430597,0.0002426654,0.00001493212,0.00001525567,0.000136182,0.0001704917,0.00002648374],"category_scores_gemma":[0.00003043049,0.0002373027,0.00007970783,0.0003585965,0.00007932242,0.00003033627,0.0000421206,0.0003661377,0.000003636844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009400359,"about_ca_system_score_gemma":0.0001134915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001788548,"about_ca_topic_score_gemma":0.001391538,"domain_scores_codex":[0.9982775,0.00006540516,0.0004637809,0.0004657321,0.0003340127,0.0003936013],"domain_scores_gemma":[0.9994745,0.00001663857,0.00004381138,0.0002211179,0.00001657393,0.0002274144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003871315,0.0002696769,0.893724,0.0001924197,0.00005400903,0.0003800937,0.006643926,0.003911302,0.003494315,0.000004940973,0.001393652,0.08954455],"study_design_scores_gemma":[0.01781775,0.0005132311,0.9314432,0.0001441012,0.0000943204,0.0000228775,0.01127397,0.01767358,0.01531127,0.0002243447,0.004851953,0.0006293773],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985589,0.008913399,0.00232975,0.001934924,0.0003210372,0.0006411705,0.00001188958,0.0000153038,0.0002435171],"genre_scores_gemma":[0.9907033,0.002865632,0.004609542,0.001648981,0.00004710159,0.00001649257,0.00002233255,0.00003328658,0.00005326161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08891518,"threshold_uncertainty_score":0.9676924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008577117520086712,"score_gpt":0.2154269554487236,"score_spread":0.2068498379286369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}