{"id":"W3092274335","doi":"10.3389/fgene.2020.01022","title":"Insulin-Independent and Dependent Glucose Transporters in Brain Mural Cells in CADASIL","year":2020,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; NIHR Newcastle Biomedical Research Centre; Newcastle upon Tyne Hospitals NHS Foundation Trust; Stiftelsen för Gamla Tjänarinnor; Engineering and Physical Sciences Research Council; Stiftelsen Olle Engkvist Byggmästare; National Institute for Health and Care Research; Alzheimer's Society; Economic and Social Research Council; Gun och Bertil Stohnes Stiftelse","keywords":"CADASIL; GLUT4; Vascular smooth muscle; Leukoencephalopathy; Biology; Internal medicine; Endocrinology; Glucose transporter; Insulin; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001128202,0.000163855,0.0001934805,0.0009601419,0.0001772236,0.0002702152,0.0001258219,0.0002846924,0.0006956609],"category_scores_gemma":[0.0001583403,0.0001176372,0.0001289381,0.0003234186,0.0002515132,0.0001236153,0.0001709223,0.0003046275,0.0001517779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001854728,"about_ca_system_score_gemma":0.00007632843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001045989,"about_ca_topic_score_gemma":0.001056098,"domain_scores_codex":[0.9999244,0.00001122644,0.000009953018,0.0000172633,0.0000203781,0.00001678125],"domain_scores_gemma":[0.9999079,0.00001375905,0.00002355201,0.000009257229,0.00001354501,0.0000319065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001744765,0.0001001977,0.02304158,0.00009784495,0.00003743642,0.0088584,0.0004764316,0.00008202327,0.9573777,0.0002619933,0.0001407728,0.007780802],"study_design_scores_gemma":[0.0001311804,0.0009556042,0.764502,0.00004885128,0.0001876435,0.02343045,0.001461786,0.001436822,0.2033911,0.001059947,0.003367376,0.00002716656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969406,0.002036216,0.0003069033,0.00004108588,0.00001436256,0.000004630205,0.0000825559,0.00001613215,0.0005574916],"genre_scores_gemma":[0.9980028,0.0009875445,0.0002506721,0.00003025325,0.00001269435,0.000005353395,0.0001874037,0.000002526754,0.0005207805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001045989,"threshold_uncertainty_score":0.002327263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008577117520086712,"score_gpt":0.2154269554487236,"score_spread":0.2068498379286369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}