{"id":"W3092285140","doi":"10.1007/s40121-020-00349-8","title":"Early Treatment of COVID-19 Disease: A Missed Opportunity","year":2020,"lang":"en","type":"article","venue":"Infectious Diseases and Therapy","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Hamilton Health Sciences; University of British Columbia","funders":"Bill and Melinda Gates Foundation","keywords":"Medicine; Clinical trial; Context (archaeology); Disease; Intensive care medicine; Pandemic; Infectious disease (medical specialty); Hepatitis C; Epidemiology; Coronavirus disease 2019 (COVID-19); Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.05277287,0.0006968268,0.002393545,0.0009084239,0.002229692,0.006120257,0.002683271,0.01272428,0.008593273],"category_scores_gemma":[0.04960401,0.0003663644,0.001478638,0.0006368152,0.01028336,0.01944708,0.004750393,0.02101202,0.002684684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00248393,"about_ca_system_score_gemma":0.009601836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00100438,"about_ca_topic_score_gemma":0.00284258,"domain_scores_codex":[0.9866981,0.007795024,0.001631435,0.0009303136,0.00216844,0.0007767844],"domain_scores_gemma":[0.9103534,0.06555233,0.004261246,0.004601279,0.009254343,0.005977398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001369789,0.000445127,0.001244771,0.005927634,0.0001708397,0.001387428,0.0018449,0.0003073747,0.002049362,0.1537295,0.4125437,0.4189795],"study_design_scores_gemma":[0.000341351,0.001639188,0.001176933,0.00743398,0.0001689364,0.001975662,0.002567504,0.0002777699,0.001049825,0.09760387,0.8856185,0.0001465197],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0008045341,0.1188565,0.001769703,0.8543029,0.02178773,0.00003580081,0.00007251175,0.00004744773,0.002322813],"genre_scores_gemma":[0.02919134,0.213279,0.007445227,0.6209641,0.1227813,0.0002386426,0.0001483377,0.0001018539,0.005850258],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.05277287,"threshold_uncertainty_score":0.2790929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1114732515040716,"score_gpt":0.4203007212507184,"score_spread":0.3088274697466468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}