{"id":"W3092306676","doi":"10.7150/thno.47435","title":"IL-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex IL-1R5/IL-1R8","year":2020,"lang":"en","type":"article","venue":"Theranostics","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Interleukin Foundation for Medical Research; Agencia Estatal de Investigación; National Institutes of Health; National Cancer Institute; Ministerio de Economía y Competitividad","keywords":"Experimental autoimmune encephalomyelitis; Multiple sclerosis; Immunology; Inflammation; Encephalomyelitis; Cytokine; Immune system; Receptor; Medicine; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003028795,0.0007587477,0.0005789276,0.0005732149,0.0001921172,0.0004086818,0.0003039041,0.0004083251,0.002485403],"category_scores_gemma":[0.000150523,0.0001388768,0.0004668029,0.0002029355,0.0004327098,0.0003305713,0.000230027,0.001127437,0.001055844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004666245,"about_ca_system_score_gemma":0.0002841745,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002631796,"about_ca_topic_score_gemma":0.0004466316,"domain_scores_codex":[0.9995466,0.00006787021,0.00004555517,0.00008033802,0.0001369279,0.0001228094],"domain_scores_gemma":[0.9998592,0.00001309932,0.00005228103,0.00001710074,0.00001673428,0.00004156771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000363161,0.00009215288,0.0001674276,0.0001034505,0.000007836385,0.00004995184,0.00001566384,0.00008692046,0.9970843,0.0001254726,0.00008812371,0.001815541],"study_design_scores_gemma":[0.0001207742,0.00205789,0.003653573,0.00003951773,0.00009710987,0.0004056308,0.0000487695,0.000891543,0.9865383,0.0001336234,0.006003287,0.000009924939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816687,0.007899333,0.005412359,0.000372618,0.000136726,0.000115233,0.0006449538,0.0003796217,0.003370501],"genre_scores_gemma":[0.9856221,0.002891615,0.006269964,0.0001552542,0.00006371189,0.0001607365,0.0007884873,0.00005053738,0.003997616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002485403,"threshold_uncertainty_score":0.00831449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03332050038402508,"score_gpt":0.2609134369008505,"score_spread":0.2275929365168254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}