{"id":"W3092316156","doi":"10.1097/tp.0000000000003476","title":"Normothermic Ex Situ Liver Perfusion Enhances Mitochondrial Function of DCD Grafts as Evidenced by High-throughput Metabolomics","year":2020,"lang":"en","type":"article","venue":"Transplantation","topic":"Organ Transplantation Techniques and Outcomes","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Cold storage; Machine perfusion; Metabolomics; Perfusion; Liver transplantation; Andrology; Glycolysis; Transplantation; Oxidative phosphorylation; Cryopreservation; Liver function; Biology; Metabolism; Medicine; Biochemistry; Internal medicine; Bioinformatics; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007251326,0.000202674,0.0003680887,0.00007676861,0.00006117502,0.000014668,0.00008997759,0.0001527126,0.0006938734],"category_scores_gemma":[0.00001627834,0.0001795202,0.0001290991,0.0002173081,0.00006147469,0.0002786227,0.000004230114,0.0001590543,0.00009235812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002501304,"about_ca_system_score_gemma":0.00006259003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001897703,"about_ca_topic_score_gemma":0.00002766274,"domain_scores_codex":[0.9986278,0.00005990099,0.0004437975,0.0003253021,0.0003704283,0.0001727498],"domain_scores_gemma":[0.9994057,0.0000796754,0.000170026,0.0001335165,0.00009631809,0.0001147826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003363356,0.00007534411,0.0007085377,0.001043301,0.00005054856,0.00002244536,0.002596991,0.00001092296,0.988436,0.0002243292,0.0004380005,0.00303027],"study_design_scores_gemma":[0.002923067,0.000951278,0.01503511,0.0001718305,0.0008810402,0.00003053559,0.0001236301,0.0001569255,0.9789019,0.00009521218,0.0005255085,0.0002039306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9202497,0.0004781898,0.0768186,0.001047221,0.0002482,0.0005901857,0.00009606175,0.0001864287,0.0002854141],"genre_scores_gemma":[0.9821385,0.01302079,0.002785645,0.001089055,0.000187608,0.00001348928,0.0005277591,0.00003148942,0.0002057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07403295,"threshold_uncertainty_score":0.7597427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01396900161019761,"score_gpt":0.2560731154391457,"score_spread":0.2421041138289481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}