{"id":"W3092355417","doi":"10.1016/j.cryobiol.2020.10.002","title":"Transient loss of membrane integrity following intracellular ice formation in dimethyl sulfoxide-treated hepatocyte and endothelial cell monolayers","year":2020,"lang":"en","type":"article","venue":"Cryobiology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Blood Services; University of Alberta","funders":"Canadian Institutes of Health Research; Canadian Blood Services","keywords":"IIf; Intracellular; Dimethyl sulfoxide; Membrane; Membrane integrity; Structural integrity; Hepatocyte; Biophysics; Cell membrane; Cryopreservation; Chemistry; Cell biology; Cell; Biochemistry; Biology; In vitro; Immunology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004746642,0.0003434802,0.0004313583,0.0001380224,0.0003823734,0.000410354,0.0004056337,0.0003989707,0.002012487],"category_scores_gemma":[0.0002339392,0.0001441375,0.0003908437,0.0002951304,0.000425829,0.0005764801,0.0002346921,0.001242171,0.0003956206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004525194,"about_ca_system_score_gemma":0.0002896484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001688602,"about_ca_topic_score_gemma":0.001748088,"domain_scores_codex":[0.9996661,0.00006127496,0.00003484576,0.00005447424,0.00007009114,0.0001133272],"domain_scores_gemma":[0.9996812,0.00007988552,0.00006670626,0.0000550687,0.00007125115,0.0000458639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005865893,0.00005548186,0.0002168525,0.00003432358,0.00001378421,0.00009467947,0.0001365188,0.00004361887,0.9980977,0.0001484977,0.00005181673,0.0005202281],"study_design_scores_gemma":[0.00001910193,0.000280624,0.004859545,0.000004485714,0.00001800855,0.00008918317,0.0001258311,0.000643308,0.9933309,0.00004045367,0.0005828221,0.000005827192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884631,0.00134132,0.005720392,0.0002448488,0.0001397105,0.00003953058,0.0007236278,0.00007153852,0.003255917],"genre_scores_gemma":[0.9943183,0.0005054218,0.002153344,0.00008616767,0.00002675222,0.00004923706,0.0007456408,0.00002426147,0.002090954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002012487,"threshold_uncertainty_score":0.006732464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01974157178862748,"score_gpt":0.2395301623208615,"score_spread":0.219788590532234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}