{"id":"W3092475087","doi":"10.15252/embr.201949499","title":"Myf6/MRF4 is a myogenic niche regulator required for the maintenance of the muscle stem cell pool","year":2020,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital; McGill University; Jewish General Hospital","funders":"Institute of Genetics; Lady Davis Institute for Medical Research; University of Ottawa; Jewish General Hospital; Government of Canada; Natural Sciences and Engineering Research Council of Canada; Ottawa Hospital Research Institute; Canadian Institutes of Health Research","keywords":"Cell biology; Biology; Stem cell; Myocyte; Skeletal muscle; Myokine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001722444,0.0001261195,0.0001514558,0.000005739861,0.0001163801,0.00000661874,0.0002359353,0.0001206285,0.00002796606],"category_scores_gemma":[0.00008736577,0.00007654752,0.0002533071,0.00008443681,0.0001319135,0.00000284675,0.0001438792,0.00007163407,0.000001991304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004964361,"about_ca_system_score_gemma":0.0001098579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001276461,"about_ca_topic_score_gemma":0.000007572944,"domain_scores_codex":[0.9989902,0.00004388781,0.0003016993,0.0003565903,0.0001024089,0.0002051595],"domain_scores_gemma":[0.9988594,0.00002580024,0.0002872244,0.0006963368,0.00007839948,0.00005281279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001905111,0.00004697795,0.000930327,0.000068872,0.00008455441,0.000004254798,0.0003093033,0.0001220121,0.9367994,0.00006540216,0.05964173,0.001736628],"study_design_scores_gemma":[0.0005888462,0.0003093658,0.01515851,0.0000165431,0.00008689355,0.0000217314,0.0003650538,0.0002737736,0.8334759,0.0005964432,0.1488771,0.0002298552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932145,0.001391598,0.0005701815,0.003075959,0.0002716499,0.0005411591,0.00002096171,0.00001108236,0.0009028449],"genre_scores_gemma":[0.9955099,0.00005447529,0.00004848466,0.00290475,0.000134556,0.00005717321,0.00001268336,0.00001915426,0.001258845],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1033235,"threshold_uncertainty_score":0.3121517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01353968612063135,"score_gpt":0.225151600178509,"score_spread":0.2116119140578777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}