{"id":"W3092492583","doi":"10.1016/j.conctc.2020.100664","title":"Evaluation of efficacy and safety of a novel lipogel containing diclofenac: A randomized, placebo controlled, double-blind clinical trial in patients with signs and symptoms of osteoarthritis","year":2020,"lang":"en","type":"article","venue":"Contemporary Clinical Trials Communications","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Osteoarthritis; Diclofenac; WOMAC; Placebo; Adverse effect; Randomized controlled trial; Drug; Clinical trial; Internal medicine; Surgery; Anesthesia; Pharmacology; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003468956,0.001797535,0.00549613,0.0009136156,0.0006687868,0.0011122,0.001184987,0.002753588,0.005466378],"category_scores_gemma":[0.001946056,0.0009208566,0.002147513,0.0007422829,0.002060762,0.001340545,0.0006515296,0.00248703,0.0008195337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004931159,"about_ca_system_score_gemma":0.001714278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003501199,"about_ca_topic_score_gemma":0.0007717762,"domain_scores_codex":[0.9987287,0.0005024277,0.0001399385,0.0003002368,0.0001752185,0.0001534741],"domain_scores_gemma":[0.9985906,0.000342902,0.0003568823,0.0001267737,0.0002019385,0.000380906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9313881,0.04351161,0.0003517654,0.00220847,0.000637682,0.00005826926,0.0001034244,0.0001792623,0.01214984,0.0001438115,0.0002925829,0.008975147],"study_design_scores_gemma":[0.7180752,0.2784998,0.000755479,0.00004943619,0.0004400065,0.00002418617,0.00003291847,0.0002914584,0.001198078,0.00008007032,0.000533167,0.00002008514],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9594573,0.007899225,0.002130534,0.0006641574,0.001267178,0.02635731,0.0008422855,0.0001423077,0.001239649],"genre_scores_gemma":[0.9398209,0.006489289,0.007021343,0.001225445,0.001239524,0.03860011,0.0009176143,0.00003509198,0.00465068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00549613,"threshold_uncertainty_score":0.01834583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3771729781775972,"score_gpt":0.4595289100118978,"score_spread":0.08235593183430068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}