{"id":"W3092591238","doi":"10.1128/msystems.00018-20","title":"Damage Repair versus Aging in an Individual-Based Model of Biofilms","year":2020,"lang":"en","type":"article","venue":"mSystems","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Centre for the Replacement, Refinement and Reduction of Animals in Research","keywords":"Multicellular organism; Biology; Soma; Senescence; Cell biology; DNA damage; Cell division; Germline; Mechanism (biology); Population; Evolutionary biology; Genetics; Cell; Neuroscience; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001651029,0.0001159264,0.0001744176,0.000035325,0.00002495198,0.00001805527,0.000128833,0.0001267187,0.000004059139],"category_scores_gemma":[0.00003518717,0.0001155592,0.00007299371,0.0001013815,0.00003379296,0.00000463165,0.00005738566,0.00006291774,0.000002316152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006827408,"about_ca_system_score_gemma":0.00006202971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006759135,"about_ca_topic_score_gemma":0.0001103562,"domain_scores_codex":[0.9991183,0.00006889079,0.0002503902,0.0002833562,0.0001008085,0.0001782239],"domain_scores_gemma":[0.9995315,0.00000668387,0.00008890477,0.0002535333,0.00003244462,0.00008691568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001767985,0.00002621145,0.003348786,0.00005840098,0.00001600136,0.000003199181,0.0001174147,0.002334681,0.993614,0.00002735522,0.0001451479,0.0001320302],"study_design_scores_gemma":[0.002213569,0.0007323454,0.001431132,0.00006430566,0.0000245505,0.000001004246,0.0002838129,0.09174674,0.9005937,9.200289e-7,0.002588767,0.000319151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989343,0.00008915619,0.0000969125,0.0001092976,0.0001600367,0.0001252903,0.00005211845,0.00002636181,0.0004064755],"genre_scores_gemma":[0.9983175,0.000003297796,0.001111641,0.0002090509,0.0001656243,0.000003235471,0.0001538514,0.00001895373,0.00001683891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09302028,"threshold_uncertainty_score":0.4712368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04855774914428094,"score_gpt":0.267233248031207,"score_spread":0.218675498886926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}