{"id":"W3092591238","doi":"10.1128/msystems.00018-20","title":"Damage Repair versus Aging in an Individual-Based Model of Biofilms","year":2020,"lang":"en","type":"article","venue":"mSystems","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Centre for the Replacement, Refinement and Reduction of Animals in Research","keywords":"Multicellular organism; Biology; Soma; Senescence; Cell biology; DNA damage; Cell division; Germline; Mechanism (biology); Population; Evolutionary biology; Genetics; Cell; Neuroscience; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000573207,0.0008146829,0.001014889,0.0007255991,0.0008395243,0.001293228,0.001791088,0.002622023,0.002870334],"category_scores_gemma":[0.001331715,0.0004201172,0.00122032,0.0004039695,0.001333449,0.001240197,0.001311498,0.001110473,0.0003839748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001440322,"about_ca_system_score_gemma":0.001227018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01548941,"about_ca_topic_score_gemma":0.007796396,"domain_scores_codex":[0.999768,0.00006456925,0.0000135543,0.00005902642,0.00004868443,0.00004618955],"domain_scores_gemma":[0.9991985,0.0002416143,0.0001870897,0.0000482352,0.0001321661,0.0001923545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001250363,0.0001604198,0.002183968,0.0001280652,0.0000804852,0.0003840236,0.0002657518,0.9004757,0.0127283,0.07869972,0.001068492,0.003700035],"study_design_scores_gemma":[0.00004328958,0.00006714054,0.0006004177,0.00001084888,0.00002533576,0.00004458858,0.00005004711,0.9879843,0.0002556238,0.01022238,0.000676925,0.00001924165],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8199916,0.001768504,0.1375388,0.003313729,0.0004141243,0.0001261132,0.000781786,0.0002260414,0.03583933],"genre_scores_gemma":[0.9712762,0.0007025544,0.01113691,0.0002101597,0.00009183209,0.0001941221,0.0001695818,0.00004817289,0.01617051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01548941,"threshold_uncertainty_score":0.03079849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04855774914428094,"score_gpt":0.267233248031207,"score_spread":0.218675498886926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}