{"id":"W3092655625","doi":"10.1093/ofid/ofaa500","title":"Safety of Hydroxychloroquine Among Outpatient Clinical Trial Participants for COVID-19","year":2020,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Alberta; Lawson Health Research Institute; McGill University Health Centre; McGill University; George & Fay Yee Centre for Healthcare Innovation; University of Manitoba","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Fogarty International Center; National Institute of Mental Health; National Cancer Institute; National Institutes of Health; Northern Alberta Clinical Trials and Research Centre; McGill University; McGill University Health Centre; Manitoba Medical Service Foundation; University of Minnesota; Gilead Sciences; Doris Duke Charitable Foundation","keywords":"Hydroxychloroquine; Medicine; Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Clinical trial; Family medicine; Internal medicine; Virology; Outbreak","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03481387,0.000650152,0.002009961,0.0003784488,0.0008145719,0.00122558,0.0008162098,0.002125361,0.005560504],"category_scores_gemma":[0.04110301,0.000445953,0.001755467,0.0007489641,0.0007687778,0.0008116717,0.0004985851,0.001642128,0.0006985702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007036686,"about_ca_system_score_gemma":0.002241956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002623371,"about_ca_topic_score_gemma":0.0006073725,"domain_scores_codex":[0.9700088,0.02329037,0.002738421,0.001545403,0.001827288,0.0005897136],"domain_scores_gemma":[0.9492801,0.01943382,0.02169324,0.003351182,0.004333483,0.00190823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7542065,0.00781116,0.07000199,0.009484854,0.005259257,0.0002613764,0.0007837597,0.0003752994,0.00957814,0.0005131727,0.009814021,0.1319105],"study_design_scores_gemma":[0.5560127,0.2323634,0.1703468,0.003074989,0.006066669,0.001217033,0.0004025646,0.00155261,0.006057869,0.001417427,0.02137212,0.0001157577],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9294867,0.03044652,0.003908042,0.002606076,0.0007114937,0.01995167,0.006252781,0.0001983459,0.006438488],"genre_scores_gemma":[0.9604099,0.003626673,0.005481055,0.002293967,0.000767934,0.02384303,0.00272192,0.00003412449,0.0008214671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03481387,"threshold_uncertainty_score":0.1841155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1833713269914755,"score_gpt":0.5051546783332369,"score_spread":0.3217833513417614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}