{"id":"W3092665778","doi":"10.3390/cells9102320","title":"Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Friends of Tel Aviv University; McGill University; Tel Aviv University; Teva Pharmaceutical Industries; National Science Foundation","keywords":"Biology; Myopathy; Gene knockdown; Myosin; Cell biology; Internal medicine; Gene; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008848787,0.0001489184,0.0001770827,0.00003228277,0.0000537256,0.000006115427,0.0002021144,0.0001506662,0.00002825048],"category_scores_gemma":[0.00008013807,0.0001576273,0.00008437801,0.0001180524,0.000113497,0.000005950714,0.0001413018,0.0001226022,0.00001070187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007157089,"about_ca_system_score_gemma":0.00003051777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004503081,"about_ca_topic_score_gemma":0.00006789742,"domain_scores_codex":[0.9988917,0.00007659676,0.0002968952,0.0004119091,0.0000774033,0.0002454903],"domain_scores_gemma":[0.999477,0.00002401725,0.0001291162,0.0002512499,0.0000343245,0.0000843427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001470153,0.000254733,0.0003762024,0.00006131348,0.000009078753,9.359174e-7,0.0006060386,0.001028687,0.9950114,0.000005030054,0.001541282,0.0009582914],"study_design_scores_gemma":[0.00173665,0.001071132,0.004426464,0.0000194253,0.00001098647,7.972709e-8,0.0008066774,0.0002943437,0.9869454,0.00007562512,0.004394726,0.000218516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885356,0.0002726098,0.0001463571,0.000124687,0.00005347547,0.0001885956,0.00006480333,0.00001717052,0.01059669],"genre_scores_gemma":[0.999163,0.00006997636,0.0001269261,0.0002099041,0.00009221229,0.000009875334,0.0001457363,0.00002131106,0.0001610783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01062737,"threshold_uncertainty_score":0.6427855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01319532314495343,"score_gpt":0.2240272638622795,"score_spread":0.2108319407173261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}