{"id":"W3092665778","doi":"10.3390/cells9102320","title":"Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Friends of Tel Aviv University; McGill University; Tel Aviv University; Teva Pharmaceutical Industries; National Science Foundation","keywords":"Biology; Myopathy; Gene knockdown; Myosin; Cell biology; Internal medicine; Gene; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001852354,0.0005219546,0.0003389869,0.0004456231,0.0002265147,0.0003957455,0.0002031293,0.0003756663,0.001742014],"category_scores_gemma":[0.0001283422,0.0002178126,0.0002978437,0.0002078916,0.0003366203,0.000203965,0.0002084599,0.0007511045,0.0005438966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003275884,"about_ca_system_score_gemma":0.0001878214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009785505,"about_ca_topic_score_gemma":0.00242317,"domain_scores_codex":[0.9997022,0.00001974867,0.00002856262,0.0001244535,0.00009646616,0.00002861499],"domain_scores_gemma":[0.9998789,0.00002290482,0.00003973667,0.00001394161,0.00001779021,0.00002686278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000233861,0.00001142809,0.0001475446,0.00001913405,0.00000509398,0.00003002688,0.000008176265,0.00004848615,0.9989653,0.00007285453,0.00004947462,0.0006191347],"study_design_scores_gemma":[0.00001045444,0.0001423496,0.004503835,0.000007555414,0.00003115873,0.000274239,0.00002901832,0.002149142,0.9893712,0.00008976389,0.003385695,0.00000560029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9483278,0.00278371,0.03837986,0.0004244058,0.0002046263,0.0001713169,0.005209315,0.0009419708,0.003557039],"genre_scores_gemma":[0.9698335,0.001636358,0.01413879,0.0002171216,0.00001789121,0.0002108893,0.003091854,0.0001876501,0.01066584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001742014,"threshold_uncertainty_score":0.005827606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01319532314495343,"score_gpt":0.2240272638622795,"score_spread":0.2108319407173261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}