{"id":"W3092733606","doi":"10.1016/j.cryobiol.2020.10.012","title":"Regulation of NF-κB, FHC and SOD2 in response to oxidative stress in the freeze tolerant wood frog, Rana sylvatica","year":2020,"lang":"en","type":"article","venue":"Cryobiology","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Oxidative stress; KEAP1; SOD2; Biology; Signal transduction; Cell biology; Gene expression; P50; SOD1; Superoxide dismutase; Molecular biology; Transcription factor; Biochemistry; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001123153,0.0001833078,0.000173659,0.000282093,0.0003346539,0.0002962634,0.0001726748,0.000220733,0.001235055],"category_scores_gemma":[0.0001002521,0.0001677752,0.0002123841,0.0001205921,0.0003861822,0.0002366892,0.0001950302,0.0004516063,0.0001356938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002037309,"about_ca_system_score_gemma":0.0001244375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001428364,"about_ca_topic_score_gemma":0.003282205,"domain_scores_codex":[0.9999233,0.00001236182,0.000003940997,0.00002547435,0.00001190274,0.0000229719],"domain_scores_gemma":[0.9998543,0.0000187328,0.00004377723,0.00001338143,0.00001794311,0.00005180368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000363066,0.00002928545,0.001603484,0.00001880483,0.000007392824,0.00004850499,0.0000632911,0.00003014068,0.9973122,0.00008604585,0.00002360856,0.0004142078],"study_design_scores_gemma":[0.00008770261,0.0006884596,0.5662881,0.00001776878,0.00008409886,0.0006782011,0.0008160688,0.001911019,0.4269241,0.0003746911,0.00210347,0.00002630072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989158,0.0003540366,0.0002737241,0.00003481841,0.000006535582,0.000003216378,0.0001383156,0.00001118533,0.0002624561],"genre_scores_gemma":[0.997497,0.0001846367,0.0003541631,0.00004068467,0.000005382085,0.00001637741,0.0002783086,0.000008812062,0.001614595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001428364,"threshold_uncertainty_score":0.004131734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01348475941773126,"score_gpt":0.244205160433158,"score_spread":0.2307204010154267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}