{"id":"W3092993804","doi":"10.1152/physiol.00012.2020","title":"Multiple Facets and Roles of Na<sup>+</sup>-K<sup>+</sup>-Cl<sup>−</sup>Cotransport: Mechanisms and Therapeutic Implications","year":2020,"lang":"en","type":"review","venue":"Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université Laval","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Cotransporter; Radiochemistry; Chemistry; Sodium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001676351,0.000850102,0.001782607,0.0001639927,0.0001983692,0.0000242049,0.0004643595,0.001039279,0.0000629861],"category_scores_gemma":[0.00002625597,0.0007535813,0.0005486417,0.0002533827,0.0003624903,0.00001484557,0.000129129,0.0004095546,0.0000173708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002803321,"about_ca_system_score_gemma":0.0002152392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002815003,"about_ca_topic_score_gemma":0.00001333816,"domain_scores_codex":[0.9966911,0.0002368498,0.0009652728,0.001305549,0.0001973468,0.0006038567],"domain_scores_gemma":[0.9983021,0.00008953612,0.0004420802,0.0007607641,0.0001634321,0.0002420985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000649233,0.0008500176,0.0004341182,0.0189187,0.003857735,0.00002202858,0.00479476,0.009342019,0.1899113,0.00307158,0.0005862739,0.7675622],"study_design_scores_gemma":[0.003279801,0.001658286,0.001746632,0.001703339,0.003073727,0.0001917013,0.0009969247,0.01100259,0.0117213,0.004201944,0.9574584,0.002965407],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07329449,0.9203678,0.002641685,0.0003281462,0.0000931004,0.001811104,0.001301959,0.00008883433,0.00007282385],"genre_scores_gemma":[0.4296935,0.5655527,0.0002372437,0.0001726686,0.0002737296,0.0002144266,0.003666227,0.000104044,0.00008550328],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9568721,"threshold_uncertainty_score":0.9994915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02256095635312104,"score_gpt":0.2689598166342178,"score_spread":0.2463988602810967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}