{"id":"W3093065321","doi":"10.1136/annrheumdis-2020-eular.401","title":"SAT0421 GUSELKUMAB DEMONSTRATED AN INDEPENDENT TREATMENT EFFECT ON FATIGUE AFTER ADJUSTMENT FOR CLINICAL RESPONSE (ACR20) IN PATIENTS WITH PSORIATIC ARTHRITIS: RESULTS FROM PHASE-3 TRIALS DISCOVER 1 & 2","year":2020,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Medicine; Psoriatic arthritis; Placebo; Internal medicine; Psoriasis; Clinical trial; Physical therapy; Concomitant; Clinical endpoint; Arthritis; Phases of clinical research; Rheumatology; Dermatology; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00187267,0.001182488,0.002239174,0.000355226,0.0002979772,0.0008118512,0.000622323,0.0009425702,0.006039619],"category_scores_gemma":[0.001477756,0.0003419511,0.003216061,0.0005615689,0.0005429956,0.0006000469,0.0003315728,0.003531848,0.00123168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005219106,"about_ca_system_score_gemma":0.0007841203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001049756,"about_ca_topic_score_gemma":0.003330777,"domain_scores_codex":[0.9993905,0.0003167311,0.00004645106,0.00008242883,0.00006590439,0.00009800828],"domain_scores_gemma":[0.9991208,0.0003213136,0.0002004137,0.0000963561,0.00007879543,0.0001822228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5949213,0.01385032,0.01367559,0.002833113,0.009818883,0.0002038584,0.0001623775,0.002164515,0.03981216,0.0003768013,0.01098653,0.3111946],"study_design_scores_gemma":[0.4432253,0.3564469,0.1624821,0.0002496504,0.007506619,0.0005834189,0.00008650446,0.002650294,0.01176796,0.0005320041,0.01432835,0.0001410679],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9665425,0.01915678,0.00114949,0.002295581,0.0005961647,0.000856069,0.004646628,0.000423986,0.004332924],"genre_scores_gemma":[0.9789444,0.006242689,0.002234658,0.00188284,0.0005484647,0.0005917777,0.005490385,0.00009179542,0.003972977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006039619,"threshold_uncertainty_score":0.02020454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1259794698293721,"score_gpt":0.3752623223085817,"score_spread":0.2492828524792096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}