{"id":"W3093483233","doi":"10.1016/j.jmb.2020.10.018","title":"Human Histone Interaction Networks: An Old Concept, New Trends","year":2020,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institutes of Health","keywords":"Histone; Histone code; Computational biology; Interactome; Nucleosome; Chromatin; Biology; Histone methylation; Histone-modifying enzymes; Genetics; DNA; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001564577,0.0001660893,0.0002676459,0.00006167233,0.00004998617,0.00002353577,0.0003072126,0.0002459319,0.00007865938],"category_scores_gemma":[0.0000272646,0.0001474715,0.000194156,0.00009772737,0.00007573515,0.000009974009,0.00008025263,0.0002754991,0.000003133744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001965413,"about_ca_system_score_gemma":0.00005948482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001201535,"about_ca_topic_score_gemma":0.000006705209,"domain_scores_codex":[0.9989129,0.00009586848,0.0005139074,0.0001805759,0.00007394682,0.0002227661],"domain_scores_gemma":[0.9989634,0.000004587568,0.0004535623,0.0001968092,0.00009294374,0.0002886643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002242706,0.00006640236,0.0002062247,0.000005851066,0.0002374812,0.00003182265,0.0002287562,0.006560192,0.922242,0.001675648,0.02737256,0.04114876],"study_design_scores_gemma":[0.0119785,0.02989263,0.001706057,0.0001073359,0.0005601572,0.001698594,0.000823962,0.01581314,0.2173201,0.004878727,0.7129179,0.002302867],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5532066,0.004334507,0.4369673,0.002738505,0.001017696,0.0001150438,0.00001024549,0.00001670125,0.001593314],"genre_scores_gemma":[0.9921338,0.00006423797,0.002278073,0.003648647,0.001529419,7.7962e-7,0.0001058871,0.00002164677,0.0002175256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7049219,"threshold_uncertainty_score":0.6013711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01428874990630913,"score_gpt":0.3017835195241621,"score_spread":0.287494769617853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}