{"id":"W3093483233","doi":"10.1016/j.jmb.2020.10.018","title":"Human Histone Interaction Networks: An Old Concept, New Trends","year":2020,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institutes of Health","keywords":"Histone; Histone code; Computational biology; Interactome; Nucleosome; Chromatin; Biology; Histone methylation; Histone-modifying enzymes; Genetics; DNA; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003792879,0.0007837972,0.001090214,0.005844284,0.000884135,0.006057545,0.00145685,0.001628413,0.00336292],"category_scores_gemma":[0.007674386,0.0006416591,0.0006396561,0.005635967,0.004288906,0.0137627,0.002219885,0.002720602,0.0009411272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002424416,"about_ca_system_score_gemma":0.001238225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001898325,"about_ca_topic_score_gemma":0.001808789,"domain_scores_codex":[0.9979736,0.0006818037,0.00009442947,0.0006529113,0.0005203765,0.00007687567],"domain_scores_gemma":[0.9916626,0.005387184,0.0005275399,0.001054603,0.0008546545,0.00051327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001430728,0.00009544504,0.0137827,0.002180456,0.0003116583,0.0002493881,0.001271553,0.006448965,0.003200633,0.5294793,0.03727339,0.4055635],"study_design_scores_gemma":[0.00001731791,0.00002974036,0.00726636,0.0005777916,0.00004996463,0.0005647765,0.0007209331,0.01783943,0.0009362104,0.7721086,0.1998365,0.0000523472],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.04327237,0.3865409,0.3940135,0.1438702,0.002040586,0.0001175741,0.005345217,0.002082255,0.02271745],"genre_scores_gemma":[0.3823037,0.2795097,0.2931611,0.01773755,0.00918173,0.0004372898,0.005415445,0.0007698924,0.01148357],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.006057545,"threshold_uncertainty_score":0.02005893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01428874990630913,"score_gpt":0.3017835195241621,"score_spread":0.287494769617853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}