{"id":"W3093567895","doi":"10.1101/2020.10.23.352898","title":"N-myristoyltransferase: Tracing Steps Backwards to Find a Way Forward","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research Institute in Oncology and Hematology; CancerCare Manitoba; University of Winnipeg","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; CancerCare Manitoba Foundation","keywords":"Myristoylation; NLS; Nuclear localization sequence; Biology; Gene; Transcription factor; Phosphorylation; Genetics; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004918529,0.0007169525,0.0004273535,0.0006281222,0.0003853425,0.001162615,0.0005154351,0.0008808655,0.001316641],"category_scores_gemma":[0.0002626595,0.0004196337,0.0004362151,0.0004985656,0.000776276,0.001702216,0.0005124393,0.001843896,0.001599291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00125819,"about_ca_system_score_gemma":0.0009498826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001038887,"about_ca_topic_score_gemma":0.001374276,"domain_scores_codex":[0.9997982,0.00002614215,0.00001677694,0.0000887529,0.00004853028,0.00002155692],"domain_scores_gemma":[0.9998596,0.00001932011,0.00003849482,0.0000261147,0.00003071299,0.00002577985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001803455,0.00005170587,0.001412409,0.0005681477,0.00003211057,0.0002802245,0.0001143732,0.0007334172,0.9221896,0.01624177,0.001789371,0.05640664],"study_design_scores_gemma":[0.00003110587,0.0002365563,0.002549589,0.0001704036,0.00006218828,0.001202426,0.000118197,0.004635345,0.8382391,0.009733276,0.142978,0.00004383774],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.4232568,0.177123,0.3308645,0.0206809,0.00244313,0.0004117992,0.002465042,0.004212521,0.0385423],"genre_scores_gemma":[0.5601531,0.08675089,0.3161762,0.001646233,0.000272383,0.0001501339,0.002291616,0.0003098555,0.0322496],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.001316641,"threshold_uncertainty_score":0.009128869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01338354111576753,"score_gpt":0.2293656147921589,"score_spread":0.2159820736763913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}