{"id":"W3093575074","doi":"10.5281/zenodo.6835758","title":"Marine organisms: a source of biomedically relevant metallo M1, M2 and M17 exopeptidase inhibitors","year":2021,"lang":"es","type":"preprint","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Exopeptidase; Proteases; Biology; Proteolysis; Aminopeptidase; Deubiquitinating enzyme; Enzyme; Ubiquitin; Biochemistry; Amino acid; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002879474,0.0004898504,0.0005637662,0.0004666176,0.0003008658,0.0007494247,0.0003567284,0.0005428492,0.002450858],"category_scores_gemma":[0.0003992498,0.0001762442,0.0003237039,0.0003903383,0.0002626294,0.0002583358,0.0006418983,0.0009114692,0.001275592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004465471,"about_ca_system_score_gemma":0.0005959978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001219843,"about_ca_topic_score_gemma":0.002458263,"domain_scores_codex":[0.9997051,0.00005704045,0.00002955584,0.00004615662,0.0001285567,0.0000334796],"domain_scores_gemma":[0.9997552,0.00003855178,0.00006194515,0.00002295381,0.00007082162,0.00005052312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004545543,0.00009664,0.001716143,0.001716766,0.0000767388,0.0004694872,0.0000815575,0.0002879129,0.9544311,0.0005503208,0.002223262,0.03789557],"study_design_scores_gemma":[0.00006120049,0.001264647,0.008934374,0.0003319217,0.000188657,0.001896921,0.0001882311,0.0006064826,0.8224925,0.0004194053,0.1635786,0.00003706747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7129924,0.2134843,0.02695486,0.004506222,0.001492649,0.0003503465,0.006331182,0.001293551,0.03259454],"genre_scores_gemma":[0.874655,0.06111225,0.02476645,0.001471796,0.0002946295,0.0002347872,0.004530861,0.0001565791,0.03277759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002450858,"threshold_uncertainty_score":0.008198917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02185330767479332,"score_gpt":0.2483145460568702,"score_spread":0.2264612383820769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}