{"id":"W3093677039","doi":"10.1093/jac/dkaa434","title":"<i>In vitro</i>assessment of CSA-131 and CSA-131 poloxamer form for the treatment of<i>Stenotrophomonas maltophilia</i>infections in cystic fibrosis","year":2020,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Infections and bacterial resistance","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Faculté de pharmacie, Université de Montréal; Istanbul Üniversitesi","keywords":"Stenotrophomonas maltophilia; Microbiology; Biofilm; Poloxamer; Antibiotics; Cytotoxicity; Cystic fibrosis; Antimicrobial; Chemistry; Pharmacology; In vitro; Bacteria; Biology; Pseudomonas aeruginosa; Medicine; Biochemistry; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002769346,0.0002975744,0.0002583133,0.0001560249,0.0001013233,0.0002017041,0.0001527372,0.0002804023,0.0009676205],"category_scores_gemma":[0.0002771415,0.0001273667,0.0002627253,0.0001477511,0.0001563877,0.0001626393,0.0001163958,0.000293129,0.0002461739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001735946,"about_ca_system_score_gemma":0.0001958276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007154622,"about_ca_topic_score_gemma":0.000878635,"domain_scores_codex":[0.9998211,0.00006520295,0.00001837529,0.00002275792,0.00004654226,0.00002613467],"domain_scores_gemma":[0.9997811,0.00006875805,0.00006322128,0.00001342934,0.00004603184,0.00002763959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004446884,0.0001183608,0.0002860251,0.0001265906,0.00001048311,0.0000431105,0.00004396405,0.0002834952,0.9958513,0.00002370674,0.00009415086,0.00267409],"study_design_scores_gemma":[0.00003007654,0.004541419,0.002490585,0.00001651635,0.00004158209,0.0001777345,0.0000298533,0.0007102686,0.9904993,0.00001017906,0.001445597,0.000006786614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926348,0.00343432,0.001513552,0.0001038819,0.00003434434,0.0001066216,0.0003185295,0.00003243551,0.001821519],"genre_scores_gemma":[0.9915412,0.002547506,0.003745182,0.00006618751,0.00002291209,0.0001198726,0.0006114317,0.00001588063,0.001329784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009676205,"threshold_uncertainty_score":0.003237009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007687631550523401,"score_gpt":0.2602348018397228,"score_spread":0.2525471702891994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}