{"id":"W3093677039","doi":"10.1093/jac/dkaa434","title":"<i>In vitro</i>assessment of CSA-131 and CSA-131 poloxamer form for the treatment of<i>Stenotrophomonas maltophilia</i>infections in cystic fibrosis","year":2020,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Infections and bacterial resistance","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Faculté de pharmacie, Université de Montréal; Istanbul Üniversitesi","keywords":"Stenotrophomonas maltophilia; Microbiology; Biofilm; Poloxamer; Antibiotics; Cytotoxicity; Cystic fibrosis; Antimicrobial; Chemistry; Pharmacology; In vitro; Bacteria; Biology; Pseudomonas aeruginosa; Medicine; Biochemistry; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001217291,0.0001393485,0.0003354483,0.00006189524,0.00004652424,0.00001479653,0.0000931082,0.00008842851,0.00001204547],"category_scores_gemma":[0.00001851298,0.00009936549,0.0002078115,0.0001375888,0.00008660248,0.00001157821,0.00001229242,0.00006777512,1.148345e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004288848,"about_ca_system_score_gemma":0.0001131438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005379806,"about_ca_topic_score_gemma":0.00002669064,"domain_scores_codex":[0.9991392,0.00003205709,0.0004610337,0.0001417821,0.00006955841,0.000156376],"domain_scores_gemma":[0.9993687,0.00005011367,0.0003139249,0.0001153619,0.000110383,0.00004150896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001322033,0.0003976379,0.001716521,0.00004780351,0.00009839072,0.000001935905,0.0001625878,0.0001079732,0.9944336,0.00001445219,0.000294069,0.001402958],"study_design_scores_gemma":[0.003372367,0.002301822,0.004201922,0.00003728983,0.00004425685,0.00003403995,0.00004122698,0.00007024887,0.9617369,0.00001905,0.0280349,0.0001060126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957106,0.0004573222,0.001473048,0.001799852,0.0001681281,0.0002933901,0.00006504616,0.000001310292,0.0000313053],"genre_scores_gemma":[0.9920336,0.004965899,0.00228178,0.0003964511,0.0002518666,0.000009649726,0.000007046431,0.0000174521,0.00003625497],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03269677,"threshold_uncertainty_score":0.4052007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007687631550523401,"score_gpt":0.2602348018397228,"score_spread":0.2525471702891994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}