{"id":"W3093807449","doi":"10.1101/2020.10.22.350991","title":"Systematic characterization and genetic interaction analysis of adhesins in <i>Candida albicans</i> virulence","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Mitacs; John S. Dunn Foundation","keywords":"Bacterial adhesin; Virulence; Candida albicans; Biology; Mutant; Corpus albicans; Microbiology; Gene; Genetics; Biofilm; Fungal protein; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002388248,0.0005321563,0.000332506,0.0005694284,0.0002153063,0.0004078553,0.0004285223,0.0002524547,0.0004801377],"category_scores_gemma":[0.0003083925,0.0001698011,0.0004179135,0.0005695739,0.00018971,0.0001283271,0.0004038273,0.0005318332,0.0002468009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003359751,"about_ca_system_score_gemma":0.0004830297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002344929,"about_ca_topic_score_gemma":0.003144898,"domain_scores_codex":[0.9996258,0.00003538633,0.00005459202,0.00006198251,0.0001685322,0.00005374949],"domain_scores_gemma":[0.9997873,0.00003868649,0.00006641326,0.0000360408,0.0000421641,0.00002942355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002136917,0.00001809789,0.0002866477,0.00001774669,0.000005314617,0.00003647756,0.000005045647,0.00006225942,0.9984302,0.00003313584,0.00003077847,0.001052894],"study_design_scores_gemma":[0.000004871526,0.000159586,0.009471088,0.00001045136,0.00004419784,0.000406244,0.00003570435,0.001030331,0.9865643,0.00002968376,0.002232346,0.00001127089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866446,0.0008119387,0.008136135,0.00009994672,0.00002153933,0.0001452909,0.002494176,0.0001868622,0.001459548],"genre_scores_gemma":[0.9809802,0.0006673431,0.01285465,0.00008377381,0.00000684646,0.00007727637,0.003741623,0.00008092116,0.001507261],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002344929,"threshold_uncertainty_score":0.004662514,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01429458950920861,"score_gpt":0.2420269940474118,"score_spread":0.2277324045382032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}