{"id":"W3093813477","doi":"10.1038/s41396-020-00805-w","title":"Autotrophic and mixotrophic metabolism of an anammox bacterium revealed by in vivo 13C and 2H metabolic network mapping","year":2020,"lang":"en","type":"article","venue":"The ISME Journal","topic":"Wastewater Treatment and Nitrogen Removal","field":"Environmental Science","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Division of Graduate Education; Biological and Environmental Research; Natural Sciences and Engineering Research Council of Canada; Division of Chemical, Bioengineering, Environmental, and Transport Systems; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; U.S. Department of Energy; Office of Science; National Science Foundation","keywords":"Anammox; Biology; Metabolic pathway; Metabolic flux analysis; Microbial metabolism; Metabolic network; Biochemistry; Autotroph; Metabolism; Citric acid cycle; Carbon fixation; Stable-isotope probing; Population; Candidatus; Bacteria; Microorganism; Chemistry; Photosynthesis; Denitrification; Nitrogen","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007257573,0.0003025396,0.0001568148,0.0003258121,0.0001914771,0.0002891085,0.000165582,0.0002611383,0.0004818777],"category_scores_gemma":[0.0000716241,0.0001745605,0.0001792059,0.0002904238,0.0001853452,0.0001774107,0.0001623222,0.0001946922,0.0001563056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002185259,"about_ca_system_score_gemma":0.0001328701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002019225,"about_ca_topic_score_gemma":0.002455818,"domain_scores_codex":[0.9999394,0.000005093616,0.000003149659,0.00002734435,0.00001245676,0.00001255319],"domain_scores_gemma":[0.9999366,0.00001133493,0.00001948897,0.000008945604,0.00001232022,0.00001147114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003957348,0.000004239867,0.0007834844,0.000009378322,0.000003518857,0.00001260704,0.000008987859,0.00009641099,0.9984341,0.00002128162,0.000005898588,0.0005804044],"study_design_scores_gemma":[0.000005600109,0.0001229998,0.0795131,0.000006407211,0.00003638,0.0001617278,0.00008570709,0.01184934,0.9072024,0.0001371637,0.0008638718,0.00001532783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955396,0.000134585,0.003194258,0.00001735358,0.000004933551,0.000006644183,0.0005302588,0.00004917737,0.0005231408],"genre_scores_gemma":[0.9932452,0.0001572448,0.005129052,0.00001667312,0.000003285205,0.00001532738,0.0007603224,0.00001931268,0.0006536053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002019225,"threshold_uncertainty_score":0.004014969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01030796792219439,"score_gpt":0.1911263797375582,"score_spread":0.1808184118153638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}