{"id":"W3093876047","doi":"10.1080/14786419.2020.1831497","title":"Catechin from <i>Burkea africana</i> Hook. Exhibits <i>in vitro</i> inhibition of human telomerase activity","year":2020,"lang":"en","type":"article","venue":"Natural Product Research","topic":"Tea Polyphenols and Effects","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Telomerase; Catechin; Telomere; In vitro; IC50; Chemistry; Polyphenol; Biology; Biochemistry; Molecular biology; DNA; Gene; Antioxidant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007167726,0.0003220175,0.0002108467,0.0003958994,0.0002554781,0.0001800601,0.00008865577,0.0002430312,0.0009993707],"category_scores_gemma":[0.0001284,0.00009101028,0.0002617018,0.0002518174,0.0001221296,0.0001417621,0.0001437737,0.0002694776,0.0001705064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001148952,"about_ca_system_score_gemma":0.0001464112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00147795,"about_ca_topic_score_gemma":0.002641696,"domain_scores_codex":[0.9999578,0.000008782661,0.000003452011,0.000008629151,0.000008072415,0.00001321012],"domain_scores_gemma":[0.9999405,0.00001479857,0.00001503572,0.000006015815,0.000008664328,0.00001489596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006577201,0.00001543365,0.0001598489,0.00005473807,0.000006556461,0.00003585541,0.00001106322,0.00002338125,0.998743,0.00001937256,0.00001564721,0.0008494035],"study_design_scores_gemma":[0.00001880369,0.000661302,0.01557314,0.000027605,0.00006131525,0.0003566934,0.00004920344,0.0002303392,0.9786898,0.00007250607,0.004252014,0.000007238305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916767,0.004828121,0.0009697081,0.0001695775,0.00003139474,0.00002876496,0.0004677039,0.00005271553,0.001775261],"genre_scores_gemma":[0.9937176,0.001589003,0.001504524,0.0001441655,0.00001528876,0.00001602804,0.0007186455,0.00001476726,0.002280001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00147795,"threshold_uncertainty_score":0.003343225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06888925250645107,"score_gpt":0.3622567260879231,"score_spread":0.293367473581472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}