{"id":"W3093948793","doi":"10.24875/aidsrev.20000005","title":"Drug-drug Interactions in Patients with HIV and Cancer in Sub-Saharan Africa","year":2021,"lang":"en","type":"review","venue":"Aids Reviews","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"National Cancer Institute; National Institutes of Health","keywords":"Drug; Dolutegravir; Medicine; Polypharmacy; Pharmacology; DrugBank; Cancer; Concomitant; Drug interaction; ANTIRETROVIRAL AGENTS; Drug repositioning; Population; Human immunodeficiency virus (HIV); Pharmacokinetics; Antiretroviral therapy; Internal medicine; Family medicine; Viral load; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006987086,0.0001662275,0.0007404863,0.0008104306,0.0004643538,0.0007772489,0.0001564631,0.0003949062,0.00391676],"category_scores_gemma":[0.003509999,0.0001274709,0.0007303749,0.002646412,0.0001435748,0.0005784486,0.0003681791,0.0007643608,0.0003333601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005377308,"about_ca_system_score_gemma":0.0009335975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003292759,"about_ca_topic_score_gemma":0.007484547,"domain_scores_codex":[0.9991985,0.0002868062,0.000199666,0.00005856175,0.0001935995,0.00006294999],"domain_scores_gemma":[0.9988487,0.0005450689,0.0004127898,0.00001798,0.0001201896,0.00005526833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001029446,0.0002471896,0.2105832,0.02086826,0.001953218,0.005192759,0.001252116,0.000516941,0.001179315,0.002284427,0.02934242,0.7255508],"study_design_scores_gemma":[0.0004078945,0.001179729,0.4280189,0.02509634,0.005007074,0.03404274,0.002772085,0.0009313933,0.001403091,0.004587481,0.4964252,0.000128114],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.09277391,0.879414,0.0005168676,0.005607889,0.0002960457,0.0001721663,0.002611848,0.00004370974,0.01856356],"genre_scores_gemma":[0.4931979,0.494864,0.002643514,0.00397583,0.0004467661,0.0001497605,0.001818312,0.00001815568,0.002885833],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00391676,"threshold_uncertainty_score":0.01310289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03691685907530889,"score_gpt":0.3299666021540348,"score_spread":0.2930497430787259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}