{"id":"W3093956495","doi":"10.2196/23830","title":"Efficacy and Safety of Inhaled Ciclesonide in Treating Patients With Asymptomatic or Mild COVID-19 in the RACCO Trial: Protocol for a Multicenter, Open-label, Randomized Controlled Trial","year":2020,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Ciclesonide; Medicine; Randomized controlled trial; Exacerbation; Clinical endpoint; Clinical trial; Pneumonia; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04512385,0.007762434,0.01164897,0.002155472,0.00377881,0.004333532,0.004430697,0.008684007,0.02755249],"category_scores_gemma":[0.03457613,0.003066277,0.005789653,0.003254375,0.004625437,0.004440801,0.002083402,0.007675529,0.006650831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004163335,"about_ca_system_score_gemma":0.01384911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001287063,"about_ca_topic_score_gemma":0.002978861,"domain_scores_codex":[0.9661573,0.02321315,0.00350752,0.00239553,0.00244821,0.002278371],"domain_scores_gemma":[0.9831733,0.003151591,0.004452344,0.002643297,0.003692857,0.002886769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9637095,0.009405311,0.0007893685,0.006463008,0.001307061,0.000152521,0.0002260153,0.000776251,0.001895744,0.001556263,0.005928734,0.007790305],"study_design_scores_gemma":[0.9610903,0.02337255,0.0013805,0.0009361291,0.0006794159,0.00004871227,0.0000794859,0.001174472,0.0005107069,0.0008647015,0.009801974,0.00006105746],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.005066355,0.0003797645,0.00144367,0.0003144145,0.0004443114,0.990351,0.001066887,0.0001070028,0.0008264408],"genre_scores_gemma":[0.005013811,0.0002194226,0.002900491,0.0003673257,0.0001334049,0.9906089,0.0003558712,0.00001080214,0.0003900073],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.04512385,"threshold_uncertainty_score":0.2386405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2134102615666061,"score_gpt":0.5419171955087796,"score_spread":0.3285069339421735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}