{"id":"W3094185885","doi":"10.1002/jcp.30120","title":"Target identification of a novel unsymmetrical 1,3,4‐oxadiazole derivative with antiproliferative properties","year":2020,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Università degli Studi di Sassari; Dalhousie Medical Research Foundation; Li Ka Shing Foundation","keywords":"KEGG; Gene; Computational biology; Biology; Tubulin; Function (biology); Chemistry; Gene ontology; Genetics; Gene expression; Microtubule","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007785425,0.0002686836,0.0004075955,0.0002993185,0.0001561602,0.0002494015,0.0001822621,0.0002695241,0.001406975],"category_scores_gemma":[0.0000898406,0.0001094643,0.0002582584,0.0003369038,0.0001026325,0.0001306079,0.0001317562,0.0003182285,0.0002704294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000373571,"about_ca_system_score_gemma":0.0003182913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009315046,"about_ca_topic_score_gemma":0.002378231,"domain_scores_codex":[0.9999275,0.000005248831,0.000003192936,0.00001909006,0.00002625555,0.00001869507],"domain_scores_gemma":[0.9999645,0.000004469283,0.00000890295,0.000003152178,0.00001003479,0.000008984483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008511449,0.00002589807,0.0002581649,0.00007660937,0.000006673107,0.0001006406,0.000008422936,0.0001727916,0.9963505,0.00006644255,0.0001265659,0.002722141],"study_design_scores_gemma":[0.00005149045,0.0005992647,0.007405714,0.000006015903,0.00005062858,0.000472055,0.00002603468,0.002394464,0.9823814,0.00005010158,0.006554088,0.000008663809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835256,0.004655132,0.006091231,0.0002572021,0.00006836685,0.0001301817,0.001553148,0.0002041781,0.003514934],"genre_scores_gemma":[0.98325,0.002303392,0.006931201,0.0001607897,0.00001601781,0.00008157788,0.002686151,0.0000246868,0.004546121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001406975,"threshold_uncertainty_score":0.0047068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03941561207332649,"score_gpt":0.2195689657581295,"score_spread":0.180153353684803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}