{"id":"W3094192068","doi":"10.1016/j.jtho.2020.09.027","title":"Neoadjuvant Chemotherapy Increases Cytotoxic T Cell, Tissue Resident Memory T Cell, and B Cell Infiltration in Resectable NSCLC","year":2020,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Janssen Biotech; Fonds de Recherche du Québec - Santé; University of Texas MD Anderson Cancer Center; Bill and Katie Weaver Charitable Trust; EMD Serono; Cancer Prevention and Research Institute of Texas; Genentech; Innovent Biologics; Astellas Pharma; Bayer Fund; Takeda Pharmaceutical Company; Ribon Therapeutics; Merck; Spectrum Pharmaceuticals; North Carolina GlaxoSmithKline Foundation; National Cancer Institute; Bayer; Exelixis; Sanofi; GlaxoSmithKline; Society for Immunotherapy of Cancer; Astellas Pharma US; Eli Lilly and Company; Bristol-Myers Squibb; AstraZeneca; Boehringer Ingelheim","keywords":"Medicine; Infiltration (HVAC); Cytotoxic T cell; Chemotherapy; Oncology; Cell; Internal medicine; Cancer research; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000103295,0.0001517085,0.000217754,0.0001345897,0.0001000211,0.0002417174,0.000070093,0.000180596,0.001663755],"category_scores_gemma":[0.0003519573,0.0001555849,0.0001035437,0.0001141857,0.0001590866,0.0001740293,0.00008988353,0.0002770913,0.0002209495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000193133,"about_ca_system_score_gemma":0.0002019173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00031183,"about_ca_topic_score_gemma":0.001033416,"domain_scores_codex":[0.9999154,0.00002432042,0.000007751467,0.00001229618,0.00002030769,0.00002004638],"domain_scores_gemma":[0.9998643,0.00004292438,0.00004047927,0.00001038675,0.000008168443,0.00003362746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01361646,0.0007692479,0.04440789,0.0002677505,0.00006090329,0.000421143,0.0001082779,0.000558186,0.902315,0.0001290868,0.001334113,0.0360119],"study_design_scores_gemma":[0.0004434415,0.02344921,0.7597194,0.00005689008,0.0002696147,0.002613318,0.0004540622,0.002263632,0.201492,0.0002505887,0.008960051,0.00002772786],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975811,0.001209996,0.0001222128,0.00007703204,0.00001949067,0.00001115449,0.00007812856,0.00002690238,0.0008738622],"genre_scores_gemma":[0.9987218,0.0003079722,0.0001295786,0.00004242648,0.0000129973,0.00001901072,0.000135942,0.000004134831,0.0006260945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001663755,"threshold_uncertainty_score":0.005565763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02015960351542771,"score_gpt":0.3554963304333422,"score_spread":0.3353367269179145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}