{"id":"W3094193803","doi":"10.2139/ssrn.3711578","title":"Developing an Aggregator Mechanism for Late-Stage Clinical Trials of Neglected Disease Product Candidates","year":2020,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Impact","funders":"","keywords":"News aggregator; Disease; Mechanism (biology); Product (mathematics); Medicine; Intensive care medicine; Clinical trial; Computer science; Internal medicine; Philosophy; Epistemology; World Wide Web; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0793883,0.001117853,0.002851313,0.00306076,0.001401778,0.00551745,0.003286188,0.003779541,0.02261721],"category_scores_gemma":[0.1405687,0.001198594,0.002040941,0.003681399,0.001296064,0.005965286,0.004494567,0.003586742,0.004436787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001854549,"about_ca_system_score_gemma":0.004773677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001238402,"about_ca_topic_score_gemma":0.001346352,"domain_scores_codex":[0.9728688,0.01941632,0.001855844,0.002147332,0.002650337,0.001061335],"domain_scores_gemma":[0.830156,0.1220756,0.014289,0.02024595,0.01024321,0.002990186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.004419554,0.0008837717,0.01639307,0.0008651961,0.0009297273,0.0007464783,0.000838239,0.08514515,0.002594918,0.4227114,0.07785862,0.3866138],"study_design_scores_gemma":[0.002253186,0.0008816415,0.003762155,0.0002481301,0.0004497973,0.0003336376,0.0001873535,0.6007826,0.00258812,0.3540801,0.0342696,0.0001637322],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.02372166,0.0005958592,0.9480826,0.008384763,0.0008766807,0.001519597,0.001370506,0.003829631,0.01161881],"genre_scores_gemma":[0.5946438,0.0005962885,0.3825749,0.00232397,0.001630278,0.002540152,0.0017198,0.0004064402,0.01356454],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.0793883,"threshold_uncertainty_score":0.4198505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5148841819696659,"score_gpt":0.5016886805426036,"score_spread":0.01319550142706227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}