{"id":"W3094248073","doi":"10.3389/fonc.2020.591843","title":"Epigenetic Mechanisms in Canine Cancer","year":2020,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ontario Genomics Institute; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Genomics; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; McGill University; Genentech; Bayer; Pfizer","keywords":"Epigenetics; Cancer; Medicine; Biology; Bioinformatics; Cancer research; Computational biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003240377,0.0004429971,0.0006157297,0.001413911,0.0002052653,0.0005723927,0.0004087045,0.0007173428,0.002279316],"category_scores_gemma":[0.0003139422,0.0001565943,0.0002819507,0.001095471,0.0003701969,0.0007315661,0.000511853,0.0009065976,0.0008995265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005419116,"about_ca_system_score_gemma":0.0006876955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00100292,"about_ca_topic_score_gemma":0.001734802,"domain_scores_codex":[0.9999077,0.00001827546,0.00001178471,0.0000223443,0.00002985068,0.00001001056],"domain_scores_gemma":[0.9998896,0.00004880085,0.00001949758,0.000003429741,0.00002852588,0.00001016857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008096048,0.00004612835,0.0003853387,0.01351214,0.00006629958,0.0003644492,0.0001076438,0.0006391337,0.007205524,0.007474968,0.02000466,0.9501127],"study_design_scores_gemma":[0.000006784252,0.00008246984,0.001221948,0.00147096,0.00007379208,0.002369001,0.00005704342,0.0001195217,0.001538294,0.002131865,0.9909113,0.00001707405],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002387493,0.998441,0.0001402252,0.0002084646,0.0001056609,0.000002702171,0.00001558679,0.000005025824,0.0008424731],"genre_scores_gemma":[0.001511206,0.9975865,0.0001281884,0.000127883,0.0001011896,0.000003076306,0.00003507385,9.301657e-7,0.0005060303],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002279316,"threshold_uncertainty_score":0.007625043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02810243519115497,"score_gpt":0.355603689305743,"score_spread":0.3275012541145881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}