{"id":"W3094370360","doi":"10.1111/bdi.13026","title":"In vivo phenotyping, mechanism‐informed treatments, domain‐based psychopathology and nomological networks: A strategy for treatment discovery and development in bipolar depression","year":2020,"lang":"en","type":"article","venue":"Bipolar Disorders","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Mood; Psychopathology; Library science; Psychology; Psychiatry; Medicine; Psychoanalysis; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001170504,0.0004461413,0.0006276252,0.0002055811,0.0001309091,0.00004058678,0.00007380948,0.0002570695,0.00003592347],"category_scores_gemma":[0.00003102047,0.0003433648,0.00009192015,0.000228653,0.0001054478,0.0001925913,0.00004902515,0.0001287549,0.000002788604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002058988,"about_ca_system_score_gemma":0.0002159133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002290799,"about_ca_topic_score_gemma":0.003277228,"domain_scores_codex":[0.9980359,0.0000853175,0.0004601451,0.0007098798,0.0001464287,0.0005623374],"domain_scores_gemma":[0.9993089,0.0001179266,0.0001007139,0.0001980662,0.00001654014,0.0002578914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002745314,0.002103446,0.6789497,0.0002110921,0.0002413928,0.00005594511,0.002214438,0.0001503406,0.001176115,0.0008595806,0.00002574502,0.311267],"study_design_scores_gemma":[0.07489303,0.008893295,0.6662211,0.00032276,0.0005297227,0.0001050602,0.002103305,0.01041564,0.002501327,0.002142818,0.2303346,0.001537395],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8298772,0.141632,0.02193201,0.002001821,0.0001175032,0.004119741,0.00008002979,0.0001052692,0.0001344377],"genre_scores_gemma":[0.9781411,0.0150996,0.005239673,0.0005986519,0.00003908735,0.0006442817,0.0001399094,0.00005072183,0.00004694146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3097296,"threshold_uncertainty_score":0.9999018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0269004177829155,"score_gpt":0.2827769898584029,"score_spread":0.2558765720754874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}